Georgetown University

This early-stage study tests the safety of combining two drugs, NEROFE and doxorubicin, in people with advanced solid tumors that have a specific genetic change (KRAS mutation) and a protein called ST2. The goal is to find the best dose and schedule. About 24 adults whose cancer …

This study tests whether a telehealth program can help cancer survivors prevent mouth sores, gum disease, and tooth decay, and improve their quality of life. About 100 cancer survivors who finished treatment at least 6 months ago will either get the telehealth program or usual ca…

This study tests whether adding azeliragon to standard chemotherapy can reduce heart damage and mental decline in women with early breast cancer. About 48 participants will receive the drug alongside chemo to see if it is safe and effective. The goal is to make cancer treatment s…

This study is for people with early-stage HPV-related throat cancer. The standard treatment is strong radiation plus chemotherapy, which can cause long-term side effects. Researchers want to see if giving only a lower dose of radiation (without chemo) works just as well to keep t…

This study tests a drug called sacituzumab govitecan in adults with advanced thymoma or thymic carcinoma that has worsened after at least one prior treatment. The main goal is to see how many patients' tumors shrink or disappear. Participants receive the drug intravenously weekly…

This study tests whether combining three drugs—daratumumab, nivolumab, and a KRAS vaccine—can control or shrink advanced pancreatic and lung cancers. About 54 adults whose cancer has worsened after standard treatment will receive the combination. The goal is to see how well the t…

This study looks at whether people with HPV-positive throat cancer who had surgery can safely receive a lower radiation dose to a smaller area (just the neck, not the original tumor site). The goal is to keep the cancer from coming back while reducing side effects. About 30 adult…

This study tests a chemotherapy drug called CPX-351 as a maintenance treatment for adults with acute myeloid leukemia (AML) who are in remission but cannot have a bone marrow transplant. The goal is to find a safe dose and see if it helps keep the cancer from coming back. About 2…

This study looks at ways to help people in Malawi keep taking their HIV prevention medicine, including a new long-acting shot that is given every two months. About 9,900 people at high risk for HIV will take part. The goal is to see if extra support helps them stay on the medicat…

This study tests a website designed to help thyroid cancer patients manage symptoms and improve quality of life after radioactive iodine (RAI) treatment. About 88 adults who had RAI in the last three years will use either the new website or a standard information site for four we…

This study is testing whether a web-based program called SHUTi can help Black/African American prostate cancer survivors sleep better. About 40 people will be randomly assigned to either the SHUTi program or an educational website. The goal is to see if the online treatment is pr…