Fundació Institut De Recerca De L'hospital De La Santa Creu I Sant Pau

This study tests whether 3D-printed models and custom surgical guides help surgeons better plan bone-cutting procedures for Kienbock disease, a condition where the lunate bone in the wrist dies due to poor blood supply. About 20 adults with stage II or III disease will receive su…

This study tests a modified dialysis method for ICU patients with acute kidney injury. The goal is to see if a special citrate-based protocol reduces the need for extra electrolytes like potassium and magnesium. About 43 adults will take part, and researchers will compare the new…

This study tests whether nicotinamide (a form of vitamin B3) can stop or reverse liver scarring in people with fatty liver disease and obesity. Thirty adults with liver fibrosis will take either nicotinamide or a placebo daily for one year. Researchers will measure changes in liv…

This study tests whether a daily dose of pravastatin, a common heart medication, can safely prolong pregnancy in women diagnosed with severe early-onset placental insufficiency. The condition restricts blood flow to the baby, often leading to early delivery. The trial will compar…

This study compares two doses of the heart medication amiodarone in people with persistent atrial fibrillation (an irregular heartbeat) after they receive an electrical shock to restore normal rhythm. The goal is to see if a lower daily dose (100 mg) works as well as the standard…

This study tests whether levetiracetam, a seizure medication, can prevent epileptic seizures in adults over 40 with Down syndrome who also have Alzheimer's disease. 120 participants will receive either the drug or a placebo for 96 weeks. The goal is to see if the drug can stop se…

This study tests whether adhesive or elastic band devices are better at securing urinary catheters in critically ill patients. Researchers will track injuries, pain, and infections in 188 adults in the ICU. The goal is to find which method causes fewer complications and more comf…

This study is testing a new psychological program called 'Feeling Safe' for 35 adults with schizophrenia or related disorders who have ongoing delusions. The goal is to see if people find the therapy acceptable and satisfying, and whether it helps reduce symptoms and improve dail…

This study tests whether adding oxytocin nasal spray to a 5-week self-compassion training program helps people with borderline personality disorder (BPD) feel better. About 80 adults with BPD will receive either the combination or training plus a placebo spray. The goal is to see…

This study tests a 'fast-track' recovery plan for children aged 2 to 17 who have surgery for a complicated appendix. The goal is to see if this plan can safely shorten hospital stays compared to standard care. About 772 children will take part, and researchers will track any comp…

This study compares two techniques used during lower back fusion surgery to reduce bleeding and pain after the operation. One method injects a numbing and blood-vessel-constricting medicine around the surgery area, while the other uses a targeted nerve block. About 62 adults havi…

This study aims to understand the expectations, attitudes, and needs of 25 adults with MASH (a liver condition linked to metabolism) before and after they join a special care program. Participants will have two interviews to share their experiences. The goal is to improve how doc…

This study aims to create and test a simple questionnaire that helps doctors and patients objectively measure the severity of chronic cough. About 100 adults aged 30 to 99, including both people with chronic cough and healthy volunteers, will fill out the questionnaire. The goal …

This study looks at whether machine learning can help predict chronic respiratory diseases like asthma and COPD. Researchers will analyze breathing test results from 50 adults to see if computer models can spot disease patterns. The goal is to improve early detection, not to test…

This study aims to see if there are different subgroups among people with type 1 diabetes by using artificial intelligence to analyze their health data. Researchers will look at clinical records and glucose monitoring information from 800 adults. Participants only need to allow a…

This study looks at 1,260 women 3 to 6 years after their first pregnancy to see how pregnancy complications like preeclampsia affect future heart health. Researchers will check blood pressure, heart function, and lifestyle factors. The goal is to create a simple app to help women…

This study looks at why people with damage to the hypothalamus or pituitary gland often have sleep problems. Researchers will compare 60 patients with healthy volunteers to measure sleep quality and levels of the hormone oxytocin. The goal is to find better ways to prevent and tr…

This study looks at 225 women who have had a miscarriage in the first 14 weeks of pregnancy to better understand why it happens. Researchers will check for genetic, hormonal, immune, and other factors, and follow participants for one year. The goal is to improve diagnosis and cre…

This study looks at how often men with inflammatory bowel disease (IBD) have human papillomavirus (HPV) in their mouth and anus. Researchers will collect samples and survey participants to find out what factors increase the risk of infection. The goal is to better understand HPV …