First Affiliated Hospital Of Chongqing Medical University

This study tests a three-drug combination (ivarmacitinib, camrelizumab, and apatinib) in 65 adults with advanced liver cancer that initially responded to immunotherapy but then stopped working. The goal is to see if adding a JAK inhibitor can re-sensitize the tumor to immune atta…

This very early study will test a drug called talquetamab in just 2 people with refractory generalized myasthenia gravis, a chronic autoimmune disease that causes severe muscle weakness and has not improved with standard treatments. Talquetamab works by directing the body's immun…

This study tests whether monoclonal antibodies can safely reduce disability during sudden attacks of neuromyelitis optica spectrum disorder (NMOSD), a rare disease that inflames the nerves and eyes. Forty adults in the acute phase of NMOSD will receive the antibody treatment, and…

This study looks at whether adding a probiotic (Lactobacillus crispatus) to the antidepressant sertraline helps teens aged 12-18 with major depression feel better. Sixty participants will receive either the probiotic or a placebo with their medication for 8 weeks. The goal is to …

This study tests a non-invasive brain stimulation method called tACS in 30 teens aged 12-18 who have first-episode depression and have never taken antidepressants. The goal is to see if tACS can safely reduce depression symptoms and improve emotional and thinking skills. Particip…

This study looks at whether selenium supplements can reduce depression symptoms in children and teenagers aged 12 to 18 who have major depressive disorder. Researchers will measure changes in depression scores over time. The goal is to find a new, simple way to help young people …

This pilot study tests whether a non-invasive brain stimulation technique called tACS can help reduce depression symptoms in adolescents aged 12-18 who are already on stable medication. The treatment involves wearing a cap that delivers a mild electrical current to the brain duri…

This study tests a fast-acting brain stimulation method called a-iTBS in 45 teens aged 12-18 with major depression. The goal is to see if it is safe, acceptable, and helps reduce depressive symptoms. Participants will receive either real or fake stimulation to compare effects.

This study looks at 120 people (patients with ureteral stricture and healthy volunteers) to find differences in gut and urine bacteria and body chemicals. Researchers hope to discover why ureteral stricture happens and find new ways to diagnose it. Participants provide stool, uri…