Eye & Ent Hospital Of Fudan University

This study tests whether giving a combination of anlotinib (a targeted therapy) and epirubicin (chemotherapy) before surgery can improve outcomes for people with advanced sinonasal adenoid cystic carcinoma, a rare and aggressive cancer of the nasal cavity and sinuses. About 76 pa…

This study looks at whether patients with a rare nasal cancer (sinonasal adenoid cystic carcinoma) can safely avoid radiation after surgery if the tumor was completely removed. About 200 patients will choose either surgery alone or surgery plus radiation, and researchers will tra…

This study tests whether injecting steroids directly into the inner ear can improve hearing in people with sudden, severe hearing loss that hasn't responded to standard treatment. Researchers will compare this method to standard steroid injections behind the eardrum. The trial in…

This study will test a new pattern of retinal laser treatment combined with anti-VEGF injections for people with proliferative diabetic retinopathy (PDR), a serious eye condition that can lead to blindness. Researchers plan to enroll 300 adults aged 18–70 with stable diabetes and…

This study compares two treatments for chronic sinusitis with nasal polyps: a less invasive surgery (simple polyp removal) combined with an anti-IL-5 drug (mepolizumab) versus extensive sinus surgery also with the drug. About 360 participants will be randomly assigned to one of t…

Researchers test whether injecting the steroid triamcinolone acetonide through the round window membrane into the inner ear can improve hearing in people with profound or complete sudden sensorineural hearing loss. The trial enrolls 56 participants aged 12 to 75 who have severe h…

This trial tests whether an 8-week internet-based cognitive behavioral therapy for insomnia (CBT-I) can reduce the distress caused by tinnitus compared with standard patient education. About 168 adults with chronic tinnitus and poor sleep will be randomly assigned to one of the t…

This study tests a conversational AI system called Fudan Tinnitus Doctor (FTD) for adults with chronic tinnitus. About 256 participants will use either the AI chatbot or a standard digital education program for 30 days. Researchers will measure changes in tinnitus severity, sleep…

This study is tracking about 1,000 adults having nasal surgery under general anesthesia to see how many experience nausea, retching, or vomiting within the first day after surgery. Researchers will also look at which patient traits, anesthesia methods, and medications might be li…

This study tests a computer algorithm (EAP-LC) that uses CT scans to predict the best path for placing a breathing tube in laryngeal cancer patients. Researchers will compare the algorithm's predictions to actual tube placement videos from 70 patients. The goal is to see if the a…