Eli Lilly And Company

This early-stage study tests a new drug called LY4152199 in adults with B-cell lymphoma that has come back or not responded to prior treatments. The drug is designed to help the body's immune cells find and attack cancer cells. The main goals are to find the safest dose and see i…

This study tests a new medicine called imlunestrant in premenopausal women with estrogen receptor-positive, HER2-negative breast cancer. Some participants will also receive ovarian suppression. The trial compares imlunestrant to tamoxifen to see how it affects cancer cells and th…

This early-stage study tests a new drug called LY4584180 in adults with certain blood cancers (like lymphoma) that have not improved after at least two prior treatments. The main goals are to check the drug's safety, how the body processes it, and whether it can shrink tumors. Ab…

This study tests a new drug called LY4005130 for adults with non-segmental vitiligo, a condition that causes white patches on the skin. About 60 people will get either the drug or a placebo through an IV to see if it safely reduces the patches. The study lasts about 48 weeks and …

This early-stage study tests a single dose of a new drug called LY3971297 in 90 adults with heart failure (either with preserved or reduced pumping ability). The main goal is to see if the drug is safe and what side effects it may cause. Participants will be monitored for about 2…

This study tests a single dose of an experimental painkiller (LY4515100) in people with moderate-to-severe pain after having their wisdom teeth removed. About 212 adults will be randomly assigned to receive either the drug or a placebo. The goal is to see if the drug reduces pain…

This study tests an experimental drug called brenipatide for adults with irritable bowel syndrome with diarrhea (IBS-D). About 531 participants will receive either the drug or a placebo as a shot under the skin. The goal is to see if it safely reduces daily abdominal pain and imp…

This study tests whether a simple headband worn at home can measure sleep stages as accurately as a full sleep lab test in people with early or symptom-free Alzheimer's. About 35 participants will wear both devices at the same time for two nights in a lab, then use the headband a…