Ecog-acrin Cancer Research Group
Clinical trials sponsored by Ecog-acrin Cancer Research Group, explained in plain language.
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Experimental combo for tough lung side effect fails to launch
Disease control TerminatedThis study tested two drugs, infliximab and intravenous immunoglobulin (IVIG), to treat a serious lung inflammation called pneumonitis that did not get better with steroids. The inflammation was a side effect of cancer immunotherapy. Only one person enrolled before the study was …
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Melanoma drug combo trial halted after just 3 patients
Disease control TerminatedThis study tested two drugs, encorafenib and binimetinib, given before surgery to people with a certain type of advanced melanoma (stage IIIB-D) that had spread to lymph nodes. The goal was to see if the drugs could shrink or eliminate the cancer before removal. The trial was sto…
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 20, 2026 11:53 UTC
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Melanoma study halted early: could a malaria drug help cancer treatment?
Disease control TerminatedThis study looked at adding hydroxychloroquine (a malaria drug) to standard targeted therapy (dabrafenib and trametinib) for people with advanced BRAF V600E/K melanoma that had high LDH levels. The goal was to see if the combination could delay cancer growth. Only 5 people enroll…
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 20, 2026 11:53 UTC