Ecog-acrin Cancer Research Group
Clinical trials sponsored by Ecog-acrin Cancer Research Group, explained in plain language.
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Drug combo aims to shrink tumors before melanoma surgery
Disease control TerminatedThis study tested whether giving two targeted drugs (encorafenib and binimetinib) before surgery could help shrink tumors in patients with stage III melanoma that had spread to their lymph nodes. The goal was to see if this approach could lead to a complete disappearance of cance…
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated Apr 04, 2026 06:51 UTC
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Could a malaria drug help fight tough skin cancer?
Disease control TerminatedThis study tested whether adding the drug hydroxychloroquine to the standard two-drug treatment (dabrafenib and trametinib) could better control advanced melanoma that has a specific genetic change (BRAF V600E/K). It aimed to see if the three-drug combo could delay cancer growth …
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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New hope for cancer patients with dangerous drug side effect
Disease control TerminatedThis study tested two drug combinations to treat severe lung inflammation (pneumonitis) in cancer patients. The inflammation was a serious side effect of certain cancer immunotherapies that didn't improve with standard steroid treatment. Researchers compared infliximab with intra…
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC