Duke University

This study tests a remote, app-enabled exercise program designed for people aged 10 to 50 with congenital heart disease. Participants use a smartphone app with exercise modules and wearable devices to track heart rate and progress. The goal is to see if this approach can safely i…

This study tested the drug empagliflozin (a diabetes medicine) in 20 people who had a kidney transplant, some with type 2 diabetes and some without. The goal was to see if the drug could help protect their heart and kidney function. The trial was stopped early, so the findings ar…

Eye pressure is usually measured with a technique called Goldmann applanation tonometry, which doctors consider the gold standard but which depends on the examiner's skill and offers limited repeatability. Researchers at Duke University are testing automated versions of this meas…

This study looks at whether yoga can improve overactive bladder symptoms in children aged 8 to 18. Participants attend a weekly yoga session for 6 weeks. Researchers will track symptom changes using questionnaires and urine tests. The goal is to find a gentle, non-drug option for…

This study tested a small device worn on the ear that uses mild electrical pulses to help control pain after a liver transplant. The goal was to see if it could reduce the need for strong painkillers like opioids. The study was stopped early and included 27 adults waiting for a l…

This study looked at whether adding dry needling (inserting thin needles into muscle knots) to standard physical therapy exercises can reduce pain and improve shoulder movement in people with frozen shoulder. Ten adults with shoulder stiffness and pain were split into two groups:…

This study looked at how applying positive or negative pressure around the body affects exercise in people with heart failure with preserved ejection fraction. 27 participants, including healthy volunteers and heart failure patients, were tested non-invasively and some invasively…

This study tests whether using expired (end-tidal) oxygen values, instead of arterial blood samples, can accurately measure the performance of pulse oximeters. Healthy adults aged 18–50 will undergo controlled oxygen desaturation sequences using a device called RespirAct, which a…

This study aimed to see if a new device called the EyeCheck monitor can measure eye pressure as accurately as standard tools in people with glaucoma or suspected glaucoma. Twenty-two participants used the device during a clinic visit. The study was stopped early, so results are l…

This study looked at whether washing out the ankle joint with salt water within 48 hours of a fracture can lower inflammation and prevent cartilage breakdown. Researchers measured chemicals in the joint fluid of 41 adults before and after surgery. The goal was to see if early cle…

This study aimed to find out how often COVID-19 affects the hearts of athletes. It planned to enroll college, professional, military, and Olympic athletes with or without COVID-19. Participants would answer daily health surveys for 30 days and share heart images for analysis. How…