Drugs For Neglected Diseases

This study tested a single-dose pill called acoziborole for sleeping sickness, a deadly parasitic disease. 208 adults with early or late-stage disease took three tablets once and were followed for 18 months. The goal was to see if the pill could cure the infection without the nee…

This study tested a single dose of the oral drug acoziborole in 35 children aged 1 to 14 with gambiense sleeping sickness, a deadly parasitic disease. The goal was to see if the drug works and is safe in children, offering a simple treatment that could help eliminate the disease.…

This study tested a new drug called LXE408 for people with primary visceral leishmaniasis, a serious parasitic disease. Fifty-two adults in Ethiopia received either LXE408 or standard treatment. The main goal was to see if the drug could cure the infection by day 28, meaning symp…

This study tested a new oral drug, LXE408, in 101 adults and adolescents with primary visceral leishmaniasis, a serious parasitic infection. Participants received one of two LXE408 regimens or a standard intravenous treatment. The goal was to see if LXE408 could safely clear the …