Changchun Genescience Pharmaceutical Co., Ltd.

This early-stage study tests a new drug called GenSci145 in people with advanced solid tumors that have a specific change in the PIK3CA gene. The goal is to see if the drug is safe, how the body processes it, and whether it can shrink tumors. About 186 adults aged 18-75 will take…

This study looks at a fertility drug called corifollitropin alfa in women aged 36 to 40 who are doing IVF. The goal is to see if the drug is safe and helps them get pregnant. About 200 women will take part, and researchers will track side effects and pregnancy success over one ye…

This study tests a new medicine called GenSci134 in children with idiopathic short stature (short height with no known cause). The trial has two parts: first, a single dose to check safety; second, multiple doses over time to see if it helps children grow faster compared to a sta…

This study tests a new oral medicine (GS3-007a) for children with growth hormone deficiency who have not yet received any growth-promoting drugs. In the first part, different doses are compared to a placebo over 14 days to find a safe dose. In the second part, the chosen dose is …

This study tests a new medicine called GenSci134 in 128 children with growth hormone deficiency, a condition where the body doesn't make enough growth hormone, leading to slow growth. The study has two parts: first, a small group of children will get a single dose to check safety…

This study tests an experimental injection called GenSci120 in 450 adults with moderate-to-severe rheumatoid arthritis who did not get enough relief from at least one standard drug. The goal is to see if the injection reduces joint swelling and pain better than a placebo or an ac…

This study tests a new oral drug (GS3-007a) to see if it can accurately diagnose adult growth hormone deficiency (AGHD). It compares the new test to the standard insulin tolerance test. About 120 adults suspected of having AGHD, plus some healthy volunteers, will take part. The g…

This early-stage trial tests the safety and tolerability of a new drug called GenSci142 for bacterial vaginosis. It involves 30 healthy Chinese women who will receive either the drug or a placebo. The main goal is to check for side effects and how the drug moves through the body.

This study tests whether adding nanocrystalline megestrol acetate to standard treatment helps improve appetite and body weight in people with advanced liver cancer who are experiencing cachexia (severe weight loss and muscle wasting). About 68 participants will be randomly assign…

This early-stage study looks at how smoking changes the way the body handles a single dose of GS1-144 tablets in healthy Chinese women who have gone through menopause. The goal is to see if smoking affects drug levels and breakdown. 24 women aged 40-65 will take part to help guid…

This early-stage study looks at how the drug GS1-144 moves through the bodies of women with liver problems compared to healthy women. About 24 women aged 18-70 will take part. The goal is to understand how liver health affects drug levels, not to treat any condition.

This early-stage study looks at how healthy postmenopausal women absorb, break down, and eliminate a single dose of the experimental drug GS1-144. Researchers will measure the drug and its byproducts in blood, urine, and stool. The goal is to understand the drug's journey through…