Centessa Pharmaceuticals (uk) Limited

This study is testing a new drug called ORX750 in people with narcolepsy or idiopathic hypersomnia—conditions that cause severe daytime sleepiness. The drug is designed to act like a natural brain protein (orexin) that helps keep people awake. Researchers will check if ORX750 is …

This study continues testing the ORX750 medication for people with narcolepsy and idiopathic hypersomnia who completed an earlier trial. It aims to understand the long-term safety and effectiveness of the drug when taken over an extended period. The research will monitor side eff…

This is an early-stage study to test the safety of a new drug called ORX142 for people who struggle with excessive daytime sleepiness. Researchers will give the drug to healthy adults, including some who are sleep-deprived, to see how their bodies handle it and if it helps them s…

This is an early-stage study to check the safety of a new oral drug called ORX489 in healthy adults. Researchers will give single and multiple doses to see how the body handles the drug and if it helps people stay awake. The main goal is to understand the drug's side effects and …