Canadian Cancer Trials Group
Clinical trials sponsored by Canadian Cancer Trials Group, explained in plain language.
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New drug combo aims to boost CAR-T power against hard-to-treat lymphoma
Disease control Not yet recruitingThis study tests whether adding two oral medications (sonrotoclax and zanubrutinib) to standard CAR-T cell therapy can improve outcomes for people with mantle cell lymphoma that has returned or not responded to prior treatment. About 40 adults whose cancer is measurable and who a…
Phase: PHASE2 • Sponsor: Canadian Cancer Trials Group • Aim: Disease control
Last updated Apr 26, 2026 20:02 UTC
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Engineered immune cells take on Hard-to-Treat tumors in early trial
Disease control Not yet recruitingThis early-phase study tests a new treatment called GCAR1, which uses a patient's own immune cells (T-cells) that are modified in a lab to recognize and attack cancer cells that have a specific marker (GPNMB). The study enrolls up to 30 people in Canada with advanced sarcoma, kid…
Phase: PHASE1 • Sponsor: Canadian Cancer Trials Group • Aim: Disease control
Last updated Apr 26, 2026 20:01 UTC
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Canadian researchers launch biobank to unlock immunotherapy secrets
Knowledge-focused Not yet recruitingThis study collects tumor tissue and blood samples from 120 cancer patients who are receiving or will receive immunotherapy. The samples are stored in a biobank for future research to better understand how these treatments work. No direct treatment is given; the goal is to gather…
Sponsor: Canadian Cancer Trials Group • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:52 UTC