Affiliated Hospital Of Nantong University

This study tests whether adding the drug QL1706 to standard chemotherapy before surgery can completely eliminate triple-negative breast cancer in 30 patients with stage II or III disease. Participants receive the combination in two phases over about 8 months, then have surgery. T…

This study tests whether a drug called mecapegfilgrastim can safely prevent moderate-to-severe myelosuppression (low blood cell counts) caused by chemotherapy and radiation for lung or esophageal cancer. About 30 adults aged 18-75 will receive the drug alongside their standard ca…

People who need emergency surgery after a traumatic event like a car crash or fall face a higher risk of developing post-traumatic stress disorder. This trial tests whether giving the sedative dexmedetomidine during surgery, with or without adding a non-invasive ear stimulation c…

Researchers are studying whether short-course preventive treatment protects high school and college freshmen with strongly positive TB skin tests from developing active tuberculosis. About 3,000 students across 26 schools in Meishan City, Sichuan Province, China, take either a 3-…

This study tests if a gentle, non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) can prevent or reduce the severe itching that often follows morphine use after cesarean section. About 104 women having a C-section will receive either rea…

This trial tests whether giving a sedative called dexmedetomidine during knee arthroscopy, along with a nerve block, can improve sleep quality in the first two days after surgery. Adults aged 18-85 scheduled for knee arthroscopy will receive either dexmedetomidine or a placebo, c…

This trial tests whether a new method of clearing mucus from the airways—using intermittent suction through a breathing tube—works better than the standard continuous suction method in comatose patients who have had a stroke. About 600 participants will be randomly assigned to on…

This study looks at whether combining a sedative drug (dexmedetomidine) with a gentle nerve stimulation technique can lower the chance of nausea and vomiting after laparoscopic surgery in women. About 176 women aged 18 to 65 having planned surgery will take part. The goal is to f…

This study tests whether monitoring changes in airway resistance can help doctors decide the best time to suction mucus from the lungs of patients on ventilators. Researchers will use machine learning to analyze data from 258 patients with conditions like ARDS or severe pneumonia…

This study looks at how gut bacteria and their byproducts affect recovery after an ischemic stroke. Researchers will compare 100 stroke patients and 100 healthy people to understand differences in gut microbes, inflammation, and immune function. The goal is to find new ways to im…