Academic And Community Cancer Research United

This study tests a drug called olaparib in 32 people with advanced bile duct cancer that has spread and has certain DNA repair gene mutations. Olaparib works by blocking enzymes that cancer cells need to grow. The main goal is to see how many patients are alive without their canc…

This study tests whether combining regorafenib (a drug that blocks cancer cell growth) with durvalumab (an immunotherapy that helps the immune system attack cancer) can shrink tumors in people with high-risk liver cancer. Four adults with stage IB to IIIA liver cancer are partici…

This study tests a personalized approach for people with early-stage Hodgkin lymphoma. Doctors use PET scans to decide if standard chemotherapy alone is enough or if adding immunotherapy drugs can improve results. The goal is to boost survival while limiting unnecessary treatment…

This study tests a combination of two drugs, nivolumab and brentuximab vedotin, in people aged 60 or older (or younger people who cannot take standard chemotherapy) with untreated Hodgkin lymphoma. The goal is to see how well this drug pair works in shrinking or eliminating the c…

This phase II trial tests whether PEA, a natural supplement, can relieve nerve pain, numbness, and tingling caused by chemotherapy in cancer patients. About 88 adults who have had nerve symptoms for at least 3 months will take PEA or a placebo for 8 weeks. The study measures chan…