Wound infection

This phase 3 trial tests whether adding a local injection of the antibiotic tobramycin to standard IV antibiotics can lower infection rates after open fracture surgery. Open fractures have a high risk of infection because the wound may not get enough blood flow for IV antibiotics…

This trial compares two surgical techniques for treating pilonidal sinus, a painful condition at the tailbone. Researchers will randomly assign 68 adults to either primary closure, where the wound is stitched closed with a drain, or the open technique, where the wound is left ope…

This study tested a special bandage (dressing) that contains a germ-killing ingredient called chlorhexidine for IV tubes placed in the arm. The goal was to see if it reduces infections and other complications compared to the standard bandage. About 300 patients in Australia and F…

This study looked at 50 adults who had emergency surgery for a belly infection (peritonitis). It compared a special vacuum dressing (NPWT) with standard wound closure to see which better prevents surgical site infections. The goal was to find a way to help wounds heal faster and …

This study tested a handheld camera that uses fluorescence to detect biofilm—a slimy layer of bacteria—in wounds. 40 adults with acute or chronic wounds were enrolled. The camera's accuracy was compared to standard lab imaging. The goal is to help doctors identify infections more…

This study tested a device called Prevena, a sterile sponge that applies gentle suction to a closed surgical wound for 5-7 days after groin surgery. The goal was to see if it lowers the chance of wound infections, reopening, or fluid leaks compared to a standard dry gauze dressin…

This study tested a special dressing coated with a spider-silk-like chemical (DACC) to see if it prevents infections after vascular surgery. Over 700 adults in the UK were randomly assigned to get either the DACC dressing or a standard one. Researchers checked for infections at 3…

This study looked at how well a special dressing called Aquacel WSF Ribbon works for healing foot ulcers and other wounds in everyday medical practice. Researchers reviewed the medical records of 214 people who used this dressing. The main goal was to see how long it took for wou…