Weaning from mechanical ventilation

This trial tests three different inspiratory muscle training programs in intensive care patients who have failed a first attempt to breathe on their own. The training uses a threshold device to strengthen the diaphragm and other breathing muscles. Researchers compare the programs…

This trial tests three breathing support methods—high-flow nasal cannula, high-velocity nasal insufflation, and noninvasive ventilation—in ICU patients at high risk of breathing failure after being taken off a ventilator. The goal is to see which approach helps patients breathe o…

This study tested whether measuring the fluid in the chest using a non-invasive device can predict if a critically ill patient is ready to have their breathing tube removed. Researchers studied 120 adults on ventilators for more than 48 hours. The goal was to see if this measurem…

This study looked at 64 adults on breathing machines to see if changes in a chest muscle (parasternal intercostal) could predict when the breathing tube could be safely removed. Researchers measured muscle thickness during breathing trials. The goal was to find a simple, non-inva…

This study tested whether a nurse-driven weaning protocol using capnography (a device that measures carbon dioxide in breath) could help safely remove breathing tubes faster in ICU patients. Fifty adults on ventilators for more than 48 hours were enrolled. Nurses followed a step-…