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New chest fluid test may predict safe breathing tube removal

NCT ID NCT06685406

Diagnosis Sponsor: Zagazig University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether measuring the fluid in the chest using a non-invasive device can predict if a critically ill patient is ready to have their breathing tube removed. Researchers studied 120 adults on ventilators for more than 48 hours. The goal was to see if this measurement could help avoid failed extubation and improve patient outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If this method proves accurate, it could give doctors a simple, non-invasive tool to decide when to safely remove a breathing tube, reducing complications.
What could go wrong
This is a small, completed study, and the results may not apply to all patients. The measurement may not be accurate in people with certain chest conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

120 people

The number who actually took part.

Started

Nov 2024

Finished

Dec 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All patient who are mechanically ventilated in ICU from both sex suffering from multi system process that may result in significant morbidity and mortality

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 2\. Patients or first degree relative's acceptance. All patients who are mechanically ventilated for more than 48 hours. 3. Gender: both sexes. 4. 5. Age: above 18 years old. Critically ill patients who suffer from multisystem diseases that can result in significant morbidity or mortality. Exclusion Criteria: \- 1. Patients with significant pleural or pericardial effusion. 2. Presence of pneumothorax or severe subcutaneous emphysema. 3. Patients with significant valvular heart lesions or atrial fibrillation. 4. Patients with injuries or wounds which hinder application of device electrodes. 5\. Presence of burns at site of application of electrodes.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiometry Thorathic fluid content Weaning from mechanical ventilation

Contacts and locations

Locations

  • Faculty of medicine, zagazig university

    Zagazig, Sharqia Province, Egypt

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