VENTRICULAR FIBRILLATION

This study tests if using two defibrillator pads in different positions and giving two quick shocks instead of one can help more people survive a cardiac arrest. It includes 916 adults whose heart stopped outside a hospital and did not respond to the first standard shock. The goa…

This study tests whether cooling the brain immediately after a cardiac arrest, using a special nasal device, helps more people survive with full brain function. About 1,000 adults aged 18-79 who have a shockable heart rhythm will be randomly assigned to either receive this ultra-…

This study looks at whether giving a lower total amount of epinephrine during resuscitation from cardiac arrest helps more people survive to leave the hospital. About 3,790 adults whose heart stops due to a shockable rhythm will be randomly assigned to receive either a low or sta…

This study tests whether a sedative called dexmedetomidine can help people with a life-threatening heart rhythm problem called electrical storm. About 192 adults in intensive care will receive either the sedative or a placebo for 2-3 days. The goal is to see if the drug reduces d…

This study looks at whether using a balloon to block the aorta (a major blood vessel) during a heart attack outside the hospital can help blood flow to the heart and brain. It involves 40 adults who are in cardiac arrest and receiving standard emergency care. The goal is to see i…

This study watches 50 adults with implanted defibrillators (ICDs) or heart failure devices (CRT-Ds) to see if a special pacing lead can accurately sense dangerous heart rhythms. Participants wear a Holter monitor at the start and after 6 months to record heart signals during rest…

This study aims to improve how we detect and understand heart disease using a new type of MRI that looks at the heart's microscopic structure. Researchers will compare these advanced scans with standard tests and blood work in 1,000 adults, both healthy volunteers and those with …