VENTILATOR ASSOCIATED PNEUMONIA (VAP)

This study looks at whether it is safe to wait for lab results before giving antibiotics to patients on breathing machines who may have pneumonia. About 686 adults in intensive care will be randomly assigned to get antibiotics right away or only after the infection is confirmed. …

This study looks at how well a new antibiotic combination, Aztreonam-Avibactam, works for hospitalized adults in China with hard-to-treat bacterial infections. About 100 patients from 30 hospitals will be observed to see if the drug clears the infection and improves recovery. The…

This study tests whether a 3-day course of inhaled colistin can prevent ventilator-associated pneumonia (VAP) in adults on breathing machines who are at high risk for drug-resistant infections. About 508 participants will receive either the drug or a placebo. The goal is to see i…

This study in a Bangladesh hospital tests whether giving ICU nurses special training and better equipment can reduce ventilator-associated pneumonia (VAP), a common infection in patients on breathing machines. Researchers will track infection rates before and after the training, …

This study follows 220 ICU patients after brain surgery to see how the balance of bacteria in their lungs changes while on a breathing machine. Researchers will collect lung fluid samples to track these changes and see if they are linked to developing pneumonia. The goal is to fi…

This study aims to develop a machine-learning tool that uses ventilator data to determine the optimal timing for suctioning secretions from the airways of patients on mechanical ventilation. Researchers will enroll 258 adults with conditions like ARDS or severe pneumonia. The goa…