VASO-OCCLUSIVE CRISIS
Clinical trials for VASO-OCCLUSIVE CRISIS explained in plain language.
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Promising drug cuts painful sickle cell crises in phase 3 trial
Disease control CompletedThis study tested a drug called inclacumab in 241 people aged 12 and older with sickle cell disease who often have painful vaso-occlusive crises. The drug works by blocking a protein that helps blood cells stick together, aiming to reduce how often these pain episodes happen. Res…
Matched conditions: VASO-OCCLUSIVE CRISIS
Phase: PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated May 26, 2026 06:50 UTC
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Oxygen chamber may ease sickle cell pain
Symptom relief CompletedThis study tested whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) could help adults with sickle cell disease feel less pain during a pain crisis and leave the hospital sooner. Eight adults with uncomplicated sickle cell pain crises received 1 to…
Matched conditions: VASO-OCCLUSIVE CRISIS
Phase: NA • Sponsor: University of Nebraska • Aim: Symptom relief
Last updated May 26, 2026 06:53 UTC
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Could laughing gas replace opioids for sickle cell pain?
Symptom relief CompletedThis small study looked at whether nitrous oxide (laughing gas) can quickly relieve severe pain in children with sickle cell disease during a vaso-occlusive crisis. Five children aged 8 to 18 who still had high pain after standard treatment received nitrous oxide in the emergency…
Matched conditions: VASO-OCCLUSIVE CRISIS
Phase: PHASE2 • Sponsor: Columbia University • Aim: Symptom relief
Last updated May 26, 2026 06:44 UTC