VASO-OCCLUSIVE CRISIS
Clinical trials for VASO-OCCLUSIVE CRISIS explained in plain language.
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Breakthrough drug trial aims to slash agonizing sickle cell pain episodes
Disease control CompletedThis completed Phase 3 trial tested whether inclacumab, given as an IV infusion every 12 weeks, could reduce the frequency of painful vaso-occlusive crises in people with sickle cell disease. The study involved 241 participants aged 12 and older who had experienced 2-10 painful c…
Matched conditions: VASO-OCCLUSIVE CRISIS
Phase: PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Laughing gas tested to ease agony of sickle cell crises
Symptom relief CompletedThis study tested nitrous oxide (laughing gas) as a potential alternative to repeated opioid painkillers for children and teens experiencing severe sickle cell pain crises. Researchers wanted to see how well and for how long the gas could relieve pain in the emergency room after …
Matched conditions: VASO-OCCLUSIVE CRISIS
Phase: PHASE2 • Sponsor: Columbia University • Aim: Symptom relief
Last updated Mar 24, 2026 12:01 UTC
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Pressurized oxygen tested to ease agony of sickle cell crisis
Symptom relief CompletedThis study explored whether a treatment called hyperbaric oxygen therapy could help adults during a sickle cell pain crisis. Eight participants received 1-3 sessions of breathing pure oxygen in a special pressurized chamber. Researchers measured if this reduced their pain and hel…
Matched conditions: VASO-OCCLUSIVE CRISIS
Phase: NA • Sponsor: University of Nebraska • Aim: Symptom relief
Last updated Mar 23, 2026 15:16 UTC