UROTHELIAL CARCINOMA

This study tested a new drug called OC-001, either by itself or combined with avelumab (an immunotherapy), in people with advanced cancers that had spread. The goal was to check safety and how the drug moves through the body. The trial was stopped early, and only 73 people were e…

This early-stage study tested a new drug called AUR106 in 21 adults with advanced cancers (lung, stomach, bladder, kidney, colon, or esophagus) that had come back or spread. The main goal was to find a safe dose and check how the drug moves through the body. The study was stopped…

This study tested whether adding the drug trilaciclib to standard chemotherapy and maintenance therapy could help people with advanced bladder cancer live longer without their disease getting worse. The trial enrolled 92 adults with untreated, advanced or metastatic urothelial ca…

This study tested different drug combinations given before surgery to remove the bladder in people with muscle-invasive bladder cancer who couldn't take the standard chemotherapy drug cisplatin. The trial was stopped early, and only 30 people took part. The main goal was to see h…

This early-stage study tested a new drug, PF-07820435, alone or with another drug (sasanlimab), in 9 people with advanced solid tumors like lung, skin, and kidney cancers. The main goal was to check safety and find the right dose. The study was stopped early, so results are limit…

This study tested a new drug called PRO1107 in 33 people with advanced solid tumors, including ovarian, endometrial, and lung cancers. The goal was to check safety and see if the drug could shrink tumors. The trial was stopped early, so results are limited.