Urothelial carcinoma
Clinical trials for Urothelial carcinoma explained in plain language.
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Can a pill target cancers with a specific gene flaw?
Disease control Not yet recruitingThis phase II trial tests an experimental drug called TR115 in people with advanced solid tumors that have a mutation in the ARID1A gene. The study includes patients with platinum-resistant ovarian clear cell carcinoma, endometrial cancer that failed immunotherapy, and other tumo…
Matched conditions: UROTHELIAL CARCINOMA
Phase 2 • Sponsor: Tarapeutics Science Inc. • Aim: Disease control
Last updated Aug 30, 2026 00:00 UTC
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New bladder cancer drug aims to fight tumors without harming nerves
Disease control Not yet recruitingThis phase II trial compares a new targeted drug, sacituzumab tirumotecan (Sac-TMT), to other antibody-drug conjugates (ADCs) in people with advanced urothelial carcinoma (bladder cancer) that has worsened after prior treatment. The main goal is to see if Sac-TMT causes less seve…
Matched conditions: UROTHELIAL CARCINOMA
Phase 2 • Sponsor: Fudan University • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New hope for tough bladder cancer: experimental drug SYS6002 faces chemo in major trial
Disease control Not yet recruitingThis phase 3 study tests a new drug called SYS6002 against standard chemotherapy in 406 people with advanced bladder cancer (urothelial carcinoma) that has worsened after platinum chemo and immunotherapy. The main goal is to see if SYS6002 helps people live longer. The study is n…
Matched conditions: UROTHELIAL CARCINOMA
Phase 3 • Sponsor: CSPC Megalith Biopharmaceutical Co.,Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New hope for advanced bladder cancer: maintenance drug aims to keep tumors in check
Disease control Not yet recruitingThis study tests whether the drug avelumab can help keep metastatic urothelial carcinoma (a type of bladder cancer) from growing after patients have already received two lines of chemotherapy. About 144 adults whose cancer has not worsened after second-line chemo will receive ave…
Matched conditions: UROTHELIAL CARCINOMA
Phase 2 • Sponsor: Gruppo Oncologico Italiano di Ricerca Clinica • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Engineered t cells take on Hard-to-Treat cancers in new trial
Disease control Not yet recruitingThis early-stage study tests a new treatment for people with advanced ovarian cancer or other solid tumors that have come back or not responded to standard therapy. The treatment uses a patient's own immune cells that are genetically modified to better recognize and attack cancer…
Matched conditions: UROTHELIAL CARCINOMA
Phase 1/2 • Sponsor: University of Chicago • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New combo therapy aims to tackle Hard-to-Treat cancers
Disease control Not yet recruitingThis study tests a new drug called CVL006 combined with standard chemotherapy or other targeted drugs in people with advanced solid tumors that have not responded to previous treatments. The trial has two phases: first, to find the safest dose, and second, to see if the combinati…
Matched conditions: UROTHELIAL CARCINOMA
Phase 1/2 • Sponsor: Convalife (Shanghai) Co., Ltd. • Aim: Disease control
Last updated Jun 26, 2026 14:20 UTC