UNRESECTABLE SOLID TUMOR
Clinical trials for UNRESECTABLE SOLID TUMOR explained in plain language.
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New drug targets tough cancers in early human trial
Disease control Recruiting nowThis early-stage study tests a new drug, RLY-2608, designed to target a specific genetic mutation (PIK3CA) found in some advanced solid tumors and breast cancers. The trial will enroll about 930 adults whose cancer has not responded to other treatments. Researchers aim to find th…
Matched conditions: UNRESECTABLE SOLID TUMOR
Phase: PHASE1 • Sponsor: Relay Therapeutics, Inc. • Aim: Disease control
Last updated May 26, 2026 02:17 UTC
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New radioactive drug targets Hard-to-Treat tumors in early trial
Disease control Recruiting nowThis study is testing an experimental radioactive drug called 177Lu-SN201 in people with advanced solid tumors that have not responded to standard treatments or for which no standard treatment exists. The drug is designed to deliver radiation directly to tumors. The main goals ar…
Matched conditions: UNRESECTABLE SOLID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Spago Nanomedical AB • Aim: Disease control
Last updated May 26, 2026 02:13 UTC
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New targeted therapy aims to control Hard-to-Treat cancers
Disease control Recruiting nowThis early-phase study tests a new drug, CLSP-1025, designed to direct immune cells to attack tumors that have a specific p53 R175H mutation. The trial enrolls adults with advanced solid tumors (like lung, colon, or pancreatic cancer) that have worsened after standard treatments.…
Matched conditions: UNRESECTABLE SOLID TUMOR
Phase: PHASE1 • Sponsor: Clasp Therapeutics, Inc. • Aim: Disease control
Last updated May 26, 2026 02:10 UTC
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New drug duo targets Hard-to-Treat cancers in early trial
Disease control Recruiting nowThis study tests whether combining two targeted drugs, pemigatinib and afatinib, is safe and works against advanced solid tumors that have certain FGFR gene changes. About 70 adults whose cancers have not responded to standard treatments will take part. The goal is to find the be…
Matched conditions: UNRESECTABLE SOLID TUMOR
Phase: PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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New pill targets Hard-to-Treat cancers with PIK3CA mutation
Disease control Recruiting nowThis early-phase study tests an experimental oral drug, RGT-490, in adults with advanced solid tumors (including breast, ovarian, and endometrial cancers) that have a specific genetic change called PIK3CA. The main goals are to check safety, find the right dose, and see if the dr…
Matched conditions: UNRESECTABLE SOLID TUMOR
Phase: PHASE1 • Sponsor: Regor Pharmaceuticals Inc. • Aim: Disease control
Last updated May 20, 2026 11:55 UTC
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New targeted drug hopes to shrink Hard-to-Treat cancers
Disease control Recruiting nowThis study tests an experimental drug called FMC-376 in people with advanced solid tumors that have a specific genetic change (KRAS G12C). The goal is to find a safe dose and see if the drug can shrink tumors. About 400 adults whose cancer has worsened after standard treatments w…
Matched conditions: UNRESECTABLE SOLID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Frontier Medicines Corporation • Aim: Disease control
Last updated May 18, 2026 12:10 UTC
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Proton GRID radiation: a new hope for painful, bulky tumors?
Symptom relief Recruiting nowThis study tests a special type of proton radiation called GRID to relieve symptoms from large tumors (at least 4.5 cm) that cannot be surgically removed or have spread. The treatment delivers high-dose radiation in a pattern of peaks and valleys, aiming to be effective while red…
Matched conditions: UNRESECTABLE SOLID TUMOR
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated May 26, 2026 02:11 UTC