UNRESECTABLE SOLID NEOPLASM
Clinical trials for UNRESECTABLE SOLID NEOPLASM explained in plain language.
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New combo therapy aims to boost immune attack on Hard-to-Treat cancers
Disease control OngoingThis early-stage study tests a new cancer vaccine (p53MVA) combined with the immunotherapy drug pembrolizumab in people with advanced solid tumors that have not responded to other treatments. The vaccine helps the immune system recognize and attack cancer cells, while pembrolizum…
Matched conditions: UNRESECTABLE SOLID NEOPLASM
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 26, 2026 09:53 UTC
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New hope for Hard-to-Treat cancers: targeted immunotherapy shows promise
Disease control OngoingThis study tests whether the immunotherapy drug nivolumab can help control advanced solid tumors that have spread or cannot be removed by surgery. It includes 16 adults whose tumors have a specific genetic change (ARID1A mutation) and a protein marker (CXCL13). The goal is to see…
Matched conditions: UNRESECTABLE SOLID NEOPLASM
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 09:53 UTC
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Experimental combo aims to outsmart resistant cancers
Disease control OngoingThis study tests whether adding the experimental drug TRC102 to standard chemotherapy (cisplatin and pemetrexed) can shrink tumors or slow cancer growth in people with advanced solid tumors or mesothelioma that have not responded to prior treatments. About 30 adults will take par…
Matched conditions: UNRESECTABLE SOLID NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 09:52 UTC
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Immunotherapy drug shows promise for rare and Hard-to-Treat cancers
Disease control OngoingThis study tests a drug called pembrolizumab (Keytruda) in 157 people with rare cancers that have spread or cannot be removed. The drug helps the immune system fight cancer by blocking a protein that tumors use to hide. The main goal is to see if the drug can stop the cancer from…
Matched conditions: UNRESECTABLE SOLID NEOPLASM
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 09:35 UTC
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Promising drug cocktail targets Hard-to-Treat ovarian cancers
Disease control OngoingThis study tests a combination of two drugs—veliparib and topotecan—in people with advanced solid tumors or ovarian cancer that has returned after initial treatment. The goal is to find the safest dose and see how well the drugs shrink tumors. About 88 adults are taking part in t…
Matched conditions: UNRESECTABLE SOLID NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 22, 2026 13:53 UTC