Unresectable or metastatic melanoma
Clinical trials for Unresectable or metastatic melanoma explained in plain language.
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New combo therapy aims to tackle melanoma that resists treatment
Disease control OngoingThis phase 2 trial is testing whether a combination of two drugs, enfortumab vedotin and pembrolizumab, can shrink tumors in people with advanced melanoma that has worsened after standard therapy. The study will enroll 60 adults with unresectable stage III or IV melanoma. Researc…
Matched conditions: UNRESECTABLE OR METASTATIC MELANOMA
Phase 2 • Sponsor: Grupo Español Multidisciplinar de Melanoma • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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New biosimilar aims to offer cheaper melanoma treatment
Disease control OngoingThis phase 3 trial is testing ABP 206, a biosimilar to the immunotherapy drug nivolumab (Opdivo), in 633 people with untreated advanced melanoma. The goal is to see if ABP 206 works just as well as nivolumab in shrinking tumors and extending life, while having a similar safety pr…
Matched conditions: UNRESECTABLE OR METASTATIC MELANOMA
Phase 3 • Sponsor: Amgen • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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New combo aims to boost immune attack on tough melanoma
Disease control OngoingThis Phase 3 trial tests whether adding HBI-8000 to the immunotherapy nivolumab helps people with advanced melanoma that has not been treated with similar drugs. About 450 participants will receive either the combo or a placebo plus nivolumab. The study also includes a separate g…
Matched conditions: UNRESECTABLE OR METASTATIC MELANOMA
Phase 3 • Sponsor: HUYABIO International, LLC. • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC