UNRESECTABLE MELANOMA
Clinical trials for UNRESECTABLE MELANOMA explained in plain language.
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New vaccine combo fights melanoma when standard treatments fail
Disease control CompletedThis study tested whether combining a new cancer vaccine (BNT111) with an existing immunotherapy drug (cemiplimab) could help patients with advanced skin cancer (melanoma) that had stopped responding to standard treatments. 184 adults with stage III or IV melanoma were assigned t…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE2 • Sponsor: BioNTech SE • Aim: Disease control
Last updated Apr 04, 2026 00:21 UTC
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Early trial tests Two-Drug attack on Tough-to-Treat skin cancer
Disease control CompletedThis early-stage study tested the safety and initial effectiveness of combining two cancer drugs, trametinib and ceritinib, in patients with advanced melanoma that could not be surgically removed. The trial involved 27 patients whose cancer had worsened despite previous standard …
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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Can a second drug boost cancer treatment power?
Disease control CompletedThis study tested whether adding the drug bevacizumab to standard immunotherapy (ipilimumab) could help patients with advanced melanoma live longer. It involved 169 adults whose cancer could not be removed by surgery. Participants were randomly assigned to receive either the sing…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC