UNRESECTABLE MELANOMA
Clinical trials for UNRESECTABLE MELANOMA explained in plain language.
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Melanoma combo fails to boost survival in trial
Disease control CompletedThis study tested whether adding bevacizumab to the immunotherapy drug ipilimumab helps people with advanced melanoma that cannot be removed by surgery. 169 adults with stage III or IV melanoma received either ipilimumab alone or ipilimumab plus bevacizumab. The combination did n…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 04:20 UTC
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New vaccine-antibody combo shows promise for hard-to-treat melanoma
Disease control CompletedThis study tested a new cancer vaccine (BNT111) combined with an immunotherapy drug (cemiplimab) in 184 people with advanced melanoma that had stopped responding to prior treatment. The goal was to see if the combination could shrink tumors better than either treatment alone. Par…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE2 • Sponsor: BioNTech SE • Aim: Disease control
Last updated May 26, 2026 04:20 UTC
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Lighter chemo before immune cell therapy shows promise in tough melanoma
Disease control CompletedThis study tested a new approach for people with advanced melanoma that cannot be removed by surgery or has spread. Doctors used a lower dose of two chemotherapy drugs (fludarabine and cyclophosphamide) to prepare the body, then infused the patient's own tumor-fighting immune cel…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE2 • Sponsor: University of Kansas Medical Center • Aim: Disease control
Last updated May 26, 2026 04:19 UTC
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New drug combo shows promise for Tough-to-Treat melanoma
Disease control CompletedThis early-phase study tested a combination of two drugs, trametinib and ceritinib, in 27 people with advanced melanoma that had not responded to previous treatments. The main goal was to find the safest dose and see if the combination could shrink tumors. While not a cure, the a…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 26, 2026 04:15 UTC
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New immune cell attack shows promise for tough melanomas
Disease control CompletedThis early-phase study tested a new treatment called TBio-4101 for people with advanced melanoma that had stopped responding to standard therapies. The treatment uses a patient's own immune cells (TILs) that are selected and grown in the lab, then given back after chemotherapy to…
Matched conditions: UNRESECTABLE MELANOMA
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 20, 2026 11:55 UTC