ULCERATIVE COLITIS (UC)

This study tests a new drug called SSGJ-627 in 288 adults with moderate to severe ulcerative colitis (UC). The goal is to see if it can safely reduce symptoms like bleeding and diarrhea. Participants must have tried other treatments without success. The drug is given in addition …

This study looks at the safety and effectiveness of the drug Velsipity (2 mg tablets) when used for up to 52 weeks in people with moderate to severe ulcerative colitis. About 553 participants will take the medicine as part of their normal care. Researchers will track serious infe…

This study tests whether the antibiotic vancomycin can safely improve symptoms of ulcerative colitis in people who also have a liver condition called primary sclerosing cholangitis. Fourteen adults will take vancomycin or a placebo for 4 weeks to see if it helps. The main goal is…

This study aims to develop digital biomarkers that can detect disease activity in people with Crohn's disease or ulcerative colitis. Researchers will collect data from smartwatches and grocery shopping habits to see if they can predict flare-ups. 80 adults on standard IBD treatme…

This study looks at whether taking 2,000 IU of vitamin D daily for 12 months can improve health and disease activity in people with Crohn's disease or ulcerative colitis. Researchers will track how well participants stick to the supplement routine and measure changes in quality o…

This study will check if a special ultrasound technique can accurately measure inflammation in people with moderate-to-severe ulcerative colitis. About 25 adults starting a new medication will get both ultrasound and a standard camera scope exam over 24 weeks. If ultrasound works…