TYPE II DIABETES MELLITUS

This study is checking how safe and well-tolerated the diabetes drug empagliflozin (taken with or without metformin) is in Pakistani adults with type 2 diabetes. About 2000 people aged 18-65 with poorly controlled blood sugar will be followed for 6 months. The study will track si…

This study tests a new treatment using special stem cells from fetal tissue for people with type 2 diabetes. The goal is to see if it is safe and can improve blood sugar control. About 30 adults with poorly controlled diabetes will receive the therapy and be monitored for side ef…

This study tests whether personalized marketing messages and discounts can encourage people with prediabetes or type 2 diabetes to switch from refined grains to whole grains when shopping for groceries online. About 216 adults aged 45-70 from the Philadelphia area who already sho…

This study tests a new weekly injection called GL0034 in 285 adults with type 2 diabetes who are overweight or obese. Participants will receive either the study drug or a placebo for about 36 weeks. The main goal is to see if GL0034 helps lower blood sugar levels more than a plac…

This study tests a new medication, CX11, for people with type 2 diabetes who need better blood sugar control despite taking metformin. About 240 adults will receive different doses of CX11 or a placebo for 24 weeks to see if it safely lowers blood sugar. The goal is to find the b…

This study tests a community-based program in rural Kabul, Afghanistan, to help prevent and control type 2 diabetes. About 250 adults aged 20 and older will take part in group learning and action meetings. The goal is to see if this approach is practical and well-liked by the com…

This study tests whether community-led learning groups can help prevent and control type 2 diabetes in rural Pakistan. Over 12,000 adults aged 20 and older from Peshawar and Swabi will take part. The approach, called Participatory Learning and Action, has worked in Bangladesh and…

This study tests whether a combination of sensory-motor exercises (like pelvic rocking and strength training) can reduce pain and improve balance in postmenopausal women with polyneuropathy. One hundred women with type 2 diabetes and numbness in their arms and legs will be random…

This early-stage study tests how a single dose of the diabetes drug GL0034 behaves in people with different levels of kidney function. About 40 adults with type 2 diabetes will be grouped by kidney health, from normal to severe impairment. Researchers will measure drug levels in …