TUBERCULOSIS, PULMONARY

This study tested a new immunotherapy called RUTI, given alongside standard antibiotics, in 41 adults with active lung tuberculosis. The goal was to see if RUTI could boost the immune system to kill both active and hidden bacteria, potentially speeding recovery and preventing dru…

This study tested a new HIV medication (Biktarvy) taken twice daily in 122 adults with both HIV and tuberculosis (TB). Participants were already on standard TB treatment. The goal was to see if the new pill could control HIV as well as the current standard treatment. Results show…

This study tested two different doses of the drug linezolid, combined with three other medicines, to treat drug-resistant tuberculosis (TB). The goal was to see if a lower dose could work just as well but with fewer side effects. 138 adults with drug-resistant TB took part, and r…

This study tested an experimental vaccine called H56:IC31 to see if it could lower the chance of tuberculosis (TB) coming back in people who had already been successfully treated. About 831 HIV-negative adults in South Africa and Tanzania took part. Half got the vaccine and half …

This study tested whether adding the RUTI vaccine to standard tuberculosis (TB) treatment helps clear the bacteria faster. It included 140 adults with drug-sensitive or multidrug-resistant TB who were already responding to standard therapy. Participants received either the vaccin…

This study compared tuberculosis patients in Benin, who received food support, with those in Togo, who did not. Researchers tracked whether nutritional help reduced treatment failure, death, or relapse. The goal is to guide future TB programs on including nutrition as part of sta…

This study tested a new rapid blood test called SeroSelectTB to see if it can diagnose active tuberculosis (TB) faster than current methods. Over 9,000 adults in South Africa, Tanzania, and Ethiopia who had symptoms of TB or pneumonia took part. The goal is to give same-day resul…

This study tested whether a thin, flexible tube with a camera (bronchoscope) can help find tuberculosis (TB) in the lungs of people whose usual spit tests came back negative. 63 adults with suspected TB took part. The goal was to see if this method could catch TB earlier and more…

This study looked at whether a supervised exercise program can improve heart and lung function and quality of life in people who have lasting health problems after tuberculosis. Sixty adults with a history of TB took part. They were split into two groups: one did the exercise pro…

This study examined 141 adults with active tuberculosis (TB) to see if intestinal parasites or poor nutrition make TB treatment less effective. Researchers tested stool samples for parasites, measured weight gain, and tracked whether patients completed TB treatment successfully. …