TRAUMA

This study tests whether placing vancomycin powder directly into the wound during spine surgery can prevent infections in patients at high risk. About 76 adults having open back surgery for spinal deformity, trauma, or tumors will take part. Half will get the powder, half will no…

This study is testing a new system for replacing failed joint implants in 105 people with conditions like arthritis, bone tumors, or previous implant failure. The main goal is to see how long the new implants last without needing another replacement. Researchers will also measure…

This study tests a therapy called FIRST, which uses five key principles to help youth manage negative emotions. Researchers will compare FIRST to usual care in 212 youth aged 7-15 with anxiety, depression, trauma, or behavior problems. The goal is to see if FIRST improves mental …

This study tests whether watching immersive 360-degree videos through a VR headset can reduce pain, anxiety, and the need for strong painkillers during dressing changes after burn surgery. About 80 adults who had skin grafts will try the VR distraction tool. The goal is to find a…

This study aimed to find the best sedative drug (propofol, etomidate, or ketamine) for putting a breathing tube in adult trauma patients. It planned to compare death rates and other outcomes. However, the study was withdrawn before enrolling anyone, so no results are available.

Many pregnant women have experienced trauma, which can make doctor visits stressful and increase health risks. This study works with patients, nurses, and doctors to create a toolkit of training and resources to help obstetric providers offer more supportive, trauma-informed care…

This study looks at how donating blood changes the heart's function, using a simple ultrasound test. Researchers will measure heart activity in 66 healthy volunteers before and after donating about a pint of blood. The goal is to see if this ultrasound method can quickly detect b…

This study was designed to see if giving calcium immediately to trauma patients receiving large blood transfusions could reduce the amount of blood products needed and improve survival. Calcium helps blood clot, which may help stop bleeding. However, the trial was withdrawn befor…

This study looks at how a gentle ultrasound pulse to the cerebellum changes brain activity and thinking in 20 healthy adults aged 18 to 40. Participants do thinking tasks after real or fake ultrasound, while their brain waves are measured. The goal is to learn how the cerebellum …

This study looks at how a serious injury or burn that requires ICU care can affect thinking and memory years later. Researchers are following 432 adults to measure long-term cognitive problems and understand how inflammation in the body might play a role. The goal is to learn why…

This study looks at whether a training program called RAPID-based psychological first aid helps people communicate better and listen more actively when helping others after a traumatic event. Ten participants who completed the training had their skills measured before and after. …