TRANSFORMED CHRONIC LYMPHOCYTIC LEUKEMIA TO DIFFUSE LARGE B-CELL LYMPHOMA
Clinical trials for TRANSFORMED CHRONIC LYMPHOCYTIC LEUKEMIA TO DIFFUSE LARGE B-CELL LYMPHOMA explained in plain language.
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New drug combo targets aggressive blood cancer in early trial
Disease control Recruiting nowThis early-phase study tests the safety and effectiveness of combining two drugs—zanubrutinib and odronextamab—in 23 adults with Richter's transformation, a fast-growing lymphoma that arises from chronic lymphocytic leukemia. Zanubrutinib blocks a protein that helps cancer grow, …
Matched conditions: TRANSFORMED CHRONIC LYMPHOCYTIC LEUKEMIA TO DIFFUSE LARGE B-CELL LYMPHOMA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 26, 2026 05:14 UTC
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New combo therapy targets tough lymphoma
Disease control Recruiting nowThis study tests a combination of two treatments—zanubrutinib (a targeted drug) and lisocabtagene maraleucel (a CAR T-cell therapy)—for people with Richter's syndrome, an aggressive lymphoma that has returned or not responded to prior treatment. About 24 participants will receive…
Matched conditions: TRANSFORMED CHRONIC LYMPHOCYTIC LEUKEMIA TO DIFFUSE LARGE B-CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Aseel Alsouqi • Aim: Disease control
Last updated May 18, 2026 12:00 UTC