T2DM
Clinical trials for T2DM explained in plain language.
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New combo pill aims to tackle diabetes and fatty liver at once
Disease control Not yet recruitingThis phase 4 trial will test whether adding alogliptin to a standard two-drug regimen (pioglitazone and metformin) improves blood sugar control and liver health in 80 adults with type 2 diabetes and fatty liver disease. Participants must not have used diabetes medications in the …
Matched conditions: T2DM
Phase: PHASE4 • Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine • Aim: Disease control
Last updated Jun 23, 2026 11:56 UTC
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Could this pill protect kidneys in diabetes?
Disease control Not yet recruitingThis study tests whether an investigational drug called HTD1801 can slow the worsening of kidney disease in adults who have both type 2 diabetes and chronic kidney disease. About 75 participants will take either HTD1801 or a placebo twice daily for 12 weeks. Researchers will meas…
Matched conditions: T2DM
Phase: PHASE2 • Sponsor: Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Jun 18, 2026 11:50 UTC
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Diabetes drug semaglutide under scrutiny for bone risks
Disease control Not yet recruitingThis study looks at whether semaglutide, a common diabetes drug, affects bone density and fracture risk in people with type 2 diabetes. Researchers will compare semaglutide plus metformin to metformin alone over 12 months in 150 adults aged 50-75. The goal is to see if the drug's…
Matched conditions: T2DM
Phase: PHASE4 • Sponsor: The First Affiliated Hospital of Xiamen University • Aim: Disease control
Last updated Jun 16, 2026 12:53 UTC
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New diabetes pill HRS9531 enters Mid-Stage trial
Disease control Not yet recruitingThis study tests whether a new tablet, HRS9531, can help control blood sugar in people with type 2 diabetes. About 240 adults who have not achieved good blood sugar control with lifestyle changes or metformin will receive either the study drug or a placebo for 20 weeks. The main …
Matched conditions: T2DM
Phase: PHASE2 • Sponsor: Fujian Shengdi Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 15, 2026 19:01 UTC
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Sleep and menopause may harm diabetic women's hearts, study warns
Knowledge-focused Not yet recruitingThis study looks at how menopause and poor sleep change heart structure and function in women aged 48-58 with type 2 diabetes. Researchers will use heart ultrasounds to measure early signs of heart strain. No treatment is given; the goal is to better understand these risks.
Matched conditions: T2DM
Sponsor: Ottawa Heart Institute Research Corporation • Aim: Knowledge-focused
Last updated May 18, 2026 12:04 UTC