SYPHILIS

This study aims to reduce sexually transmitted infections like chlamydia and gonorrhea among Black youth aged 15–26 in New Orleans. Participants receive free testing for four STIs, and those who test positive get counseling and treatment options for themselves and their partners.…

This study compares two antibiotics—cefixime (a pill) and penicillin G (a shot)—for treating early syphilis in 400 adults, including those with well-controlled HIV. The goal is to see if the pill works as well as the standard shot. Participants must have a positive blood test and…

This study is checking if a new rapid test (using a fingerstick blood sample) can accurately diagnose syphilis on the spot, compared to standard lab tests. About 1,300 people visiting a sexual health clinic in Ottawa will take part. If proven reliable, this quick test could help …

This study evaluates a new point-of-care test called MagIA H3S that can detect HIV, hepatitis B, hepatitis C, and syphilis from a single blood sample. Researchers will test about 2,950 people in Ivory Coast and Kenya to see how accurate the device is compared to standard lab test…

This study aims to see if newer, more precise lab tests can detect syphilis better than current methods in pregnant women and their newborns. Researchers will compare two molecular tests to the standard CDC guidelines using samples taken around birth. About 924 participants will …

This study offers routine and rapid syphilis testing to pregnant women who come to the emergency room or obstetrical triage without having had prenatal care or a syphilis test during their pregnancy. The goal is to increase the number of women who get full treatment and ensure bo…

This study tests whether taking the antibiotic doxycycline shortly after sex (called doxy-PEP) can prevent bacterial STIs like syphilis, gonorrhea, and chlamydia. It involves 200 sexual and gender minorities in Rio de Janeiro who are living with HIV or taking PrEP. Participants c…

This study tests whether taking the antibiotic doxycycline can prevent bacterial sexually transmitted infections (STIs) like chlamydia, gonorrhea, and syphilis in adolescent and young adult females aged 13-29 who are at high risk. About 760 participants will be randomly assigned …

This study looks at how syphilis bacteria spread in women and men who have sex with women only. Researchers want to know if the bacteria can be found in places without sores, and if it's alive enough to infect others. About 480 people with early syphilis will give extra swabs and…