Symptomatic apical periodontitis
Clinical trials for Symptomatic apical periodontitis explained in plain language.
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Could a cold rinse and diabetes drug soothe root canal pain?
Symptom relief CompletedThis study tested whether rinsing the tooth with cold saline (cryotherapy) or placing metformin (a diabetes drug) inside the tooth can reduce pain after root canal treatment. 80 adults with infected lower premolars were randomly assigned to receive one of four treatments. Pain wa…
Matched conditions: SYMPTOMATIC APICAL PERIODONTITIS
Sponsor: Celalettin Topbaş • Aim: Symptom relief
Last updated Sep 18, 2026 00:00 UTC
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Ice pack or cold rinse: simple trick to beat root canal pain?
Symptom relief CompletedThis study tested whether applying cold therapy (cryotherapy) inside the mouth or inside the tooth itself can reduce pain and inflammation after root canal treatment. Thirty adults with painful tooth infections received either an oral cold pack, a cold saline rinse inside the too…
Matched conditions: SYMPTOMATIC APICAL PERIODONTITIS
Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Jaw disorder may worsen root canal pain, study finds
Knowledge-focused CompletedThis study looked at whether a common jaw joint disorder (anterior disc displacement with reduction) affects pain after root canal treatment. 70 adults with tooth infection and jaw pain were treated and tracked their pain for a week. The goal is to see if dentists should consider…
Matched conditions: SYMPTOMATIC APICAL PERIODONTITIS
Sponsor: Recep Tayyip Erdogan University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC