SURGICAL SITE INFECTION (SSI)
Clinical trials for SURGICAL SITE INFECTION (SSI) explained in plain language.
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One day of antibiotics may be enough after bone nail surgery
Disease control CompletedThis study looked at whether a one-day course of antibiotics works as well as a three-day course to prevent infections after surgery for broken thigh or shin bones. Fifty-six adults who had a metal rod placed inside the bone were randomly assigned to receive antibiotics for eithe…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Kathmandu University School of Medical Sciences • Aim: Disease control
Last updated May 26, 2026 12:12 UTC
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Drain or rinse? study tests best way to stop C-Section infections in obese women
Prevention CompletedThis study looked at 189 women with obesity who had a C-section to see which method better prevents wound infections: placing a small drain under the skin or rinsing the wound with salt water. Both methods were compared to standard skin closure alone. The goal was to find a simpl…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Ain Shams University • Aim: Prevention
Last updated May 26, 2026 12:09 UTC
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Tailored antibiotics cut infection risk after pancreatic surgery
Prevention CompletedThis study looked at 117 adults who had pancreatic surgery after having a bile duct stent. It compared two different antibiotics given before surgery to prevent wound infections. The goal was to see if using a stronger antibiotic based on local germ patterns works better than the…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Sponsor: Central Hospital, Nancy, France • Aim: Prevention
Last updated May 26, 2026 12:03 UTC
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Wound antibiotics may cut surgery infections
Prevention CompletedThis study tested whether placing antibiotics directly into the surgical wound, in addition to standard IV antibiotics, could reduce infections after surgery. 284 adults having elective procedures like hernia repair or gallbladder removal took part. The goal was to see if the com…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Lahore General Hospital • Aim: Prevention
Last updated May 18, 2026 12:10 UTC
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Foam vs gauze: which C-Section dressing heals better?
Symptom relief CompletedThis study tested whether a polyurethane foam dressing leads to better scar appearance and fewer infections than a standard gauze dressing after cesarean delivery. Two hundred women who had C-sections were randomly assigned to one of the two dressings. Researchers checked scar qu…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Yewon Jung • Aim: Symptom relief
Last updated May 26, 2026 12:12 UTC
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Heart surgery patients get faster healing with own blood plasma
Symptom relief CompletedThis study tested whether applying a patient's own platelet-rich plasma (PRP) to the chest wound during heart surgery reduces infections and improves healing. 98 adults having open-heart surgery were randomly assigned to receive either PRP plus standard closure or standard closur…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Shaheed Zulfiqar Ali Bhutto Medical University • Aim: Symptom relief
Last updated May 26, 2026 12:06 UTC
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More wires, more infection risk in thigh bone surgery, study finds
Knowledge-focused CompletedThis study reviewed 148 patients who had thigh bone or hip replacement-related fracture surgery using metal wires (cerclage) to hold bone pieces together. Researchers found that the more wires used, the higher the chance of deep infection or persistent wound drainage. The key tak…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 26, 2026 12:07 UTC
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Stitch style may prevent hernia after belly surgery
Knowledge-focused CompletedThis study looked at 217 adults who had abdominal surgery to see how different incision and stitching methods affect the chance of developing an incisional hernia—a common complication that can cause pain and need more surgery. Researchers compared a newer "small-bite" stitching …
Matched conditions: SURGICAL SITE INFECTION (SSI)
Sponsor: Muğla Sıtkı Koçman University • Aim: Knowledge-focused
Last updated May 19, 2026 11:58 UTC
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Do you really need sterile gloves for wound care? small study investigates
Knowledge-focused CompletedThis pilot study looked at 25 adults who had knee surgery to see if using clean non-sterile gloves for wound dressing leads to more infections than sterile gloves. Over six weeks, researchers tracked infections and other outcomes like hospital stay length and costs. The goal was …
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Hamad Medical Corporation • Aim: Knowledge-focused
Last updated May 18, 2026 12:04 UTC