SUBARACHNOID HEMORRHAGE, ANEURYSMAL

This study tests a non-invasive treatment called remote ischemic conditioning (RIC) for people recovering from a serious brain bleed (aneurysmal subarachnoid hemorrhage) after surgery. RIC uses a blood pressure cuff on the arm to create brief, harmless blood flow interruptions, w…

This study is testing a non-invasive device that stimulates the vagus nerve (a key nerve in the body) to see if it is safe and helpful for people who have had a brain bleed from a burst aneurysm. The device is placed on the neck and delivers gentle electrical pulses. Researchers …

This study tests a treatment called remote ischemic conditioning (RIC) for people who have had a brain aneurysm bleed. RIC involves briefly inflating a blood pressure cuff on the arm to restrict blood flow, which may protect the brain. The study will compare recovery and brain da…

This study tests whether delivering lidocaine (with or without steroids) directly into an artery in the brain can relieve the severe headaches that often follow a type of stroke called subarachnoid hemorrhage. The goal is to reduce pain and the need for strong opioid drugs. About…

This study tests whether a numbing injection in the face can reduce severe headaches and the need for strong painkillers after a brain bleed. About 195 adults who had a brain bleed will receive either the active injection or a placebo. The goal is to see if this approach safely c…

This study looks at how the antibiotic telavancin moves into the brain fluid of critically ill patients who have had a brain bleed and have a drain in their head. Twenty adults aged 18 to 85 will receive three doses of telavancin, and researchers will measure the drug levels in t…

This study looks at a condition called augmented renal clearance (ARC), where the kidneys work too fast and remove medications too quickly. It focuses on adults in the intensive care unit with life-threatening brain problems like stroke, severe injury, or infection. Researchers w…

This study looks at people who had a specific type of brain bleed (aneurysmal subarachnoid hemorrhage) to see if their memory problems are linked to a smaller hippocampus, a brain area important for memory. Researchers will use MRI scans and memory tests to compare patients with …

This study looks at how much nimodipine, the only proven drug for brain aneurysm bleeds, actually gets into patients' blood. Researchers will measure drug levels in 500 adults across Canada and the US and check their recovery 90 days later. The goal is to understand why some pati…