STIFF PERSON SYNDROME
Clinical trials for STIFF PERSON SYNDROME explained in plain language.
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Could a stem cell transplant halt autoimmune attacks on the brain?
Disease control OngoingThis study tests a strong chemotherapy combination followed by a stem cell transplant in people with autoimmune neurologic diseases like multiple sclerosis or stiff person syndrome that haven't responded to standard treatments. The goal is to weaken the overactive immune system s…
Matched conditions: STIFF PERSON SYNDROME
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 26, 2026 03:20 UTC
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CAR t therapy takes on rare muscle-stiffening disease
Disease control OngoingThis study tests a new treatment called KYV-101 for people with stiff person syndrome, a rare disease that causes severe muscle stiffness and spasms. The treatment uses a patient's own immune cells, modified to target and calm the immune system. The study will enroll 25 adults to…
Matched conditions: STIFF PERSON SYNDROME
Phase: PHASE2 • Sponsor: Kyverna Therapeutics • Aim: Disease control
Last updated May 26, 2026 03:09 UTC
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Engineered immune cells take on lupus and scleroderma in early trial
Disease control ENROLLING_BY_INVITATIONThis early-phase study tests a new treatment called Prula-cel for people with certain autoimmune diseases like lupus and scleroderma. Prula-cel uses specially engineered immune cells from a healthy donor to target and attack faulty immune cells that cause disease. The main goals …
Matched conditions: STIFF PERSON SYNDROME
Phase: PHASE1 • Sponsor: Adicet Therapeutics • Aim: Disease control
Last updated May 08, 2026 12:02 UTC