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Engineered immune cells take on lupus and scleroderma in early trial

NCT ID NCT06375993

First seen Mar 31, 2026 · Last updated Apr 29, 2026 · Updated 2 times

Summary

This early-phase study tests a new treatment called Prula-cel for people with autoimmune diseases like lupus, scleroderma, and vasculitis. Prula-cel uses specially engineered immune cells from a donor to target and attack faulty B cells that drive the disease. The main goals are to find a safe dose and check for side effects in about 180 adults.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Adicet Clinical Trials

    Redwood City, California, 94065, United States

  • Roswell Park Comprehensive Cancer Center

    Buffalo, New York, 14263, United States

Conditions

Explore the condition pages connected to this study.