STAGE IVA LARYNGEAL CANCER AJCC V8
Clinical trials for STAGE IVA LARYNGEAL CANCER AJCC V8 explained in plain language.
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New trial aims to refine treatment for advanced head and neck cancer
Disease control Recruiting nowThis study compares radiation therapy alone to radiation plus the chemotherapy drug cisplatin in patients with stage III-IVA head and neck cancer who have had surgery. The goal is to see which approach better prevents the cancer from returning. About 189 participants will be enro…
Matched conditions: STAGE IVA LARYNGEAL CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 01, 2026 15:43 UTC
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New drug combo could shrink head and neck tumors before surgery
Disease control Recruiting nowThis study tests whether adding an experimental drug (CDX-1140) to a standard immunotherapy (cemiplimab) before surgery can shrink tumors more than the immunotherapy alone in people with stage III-IV head and neck cancer. About 44 participants will receive either the combination …
Matched conditions: STAGE IVA LARYNGEAL CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 01, 2026 15:41 UTC
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New combo therapy aims to boost survival in returning head and neck cancer
Disease control Recruiting nowThis study tests whether adding chemotherapy or a chemo-immunotherapy combination before standard salvage surgery helps people with a specific type of head and neck cancer that has come back or persisted. About 180 adults with PD-L1 positive cancer will be randomly assigned to on…
Matched conditions: STAGE IVA LARYNGEAL CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 30, 2026 15:50 UTC
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New drug combo aims to boost chemoradiation for head and neck cancer
Disease control Recruiting nowThis early-phase study tests whether adding the experimental drug ipatasertib to standard chemotherapy and radiation is safe for people with advanced head and neck cancer. Ipatasertib may help stop cancer cells from growing. The study involves about 46 adults and aims to find the…
Matched conditions: STAGE IVA LARYNGEAL CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 30, 2026 15:50 UTC
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New scan method reveals hidden radiation damage to neck arteries
Knowledge-focused Recruiting nowThis study aims to see if a special PET/CT scan using sodium fluoride can better detect radiation damage to neck blood vessels than the standard scan in 20 adults with head and neck cancers. Participants will get both types of scans before and after radiation therapy. The goal is…
Matched conditions: STAGE IVA LARYNGEAL CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: Emory University • Aim: Knowledge-focused
Last updated May 01, 2026 15:38 UTC