STAGE IV LUNG CANCER AJCC V8
Clinical trials for STAGE IV LUNG CANCER AJCC V8 explained in plain language.
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Lung cancer combo shows promise but study cut short
Disease control TerminatedThis study tested whether adding an immunotherapy drug (bintrafusp alfa) to standard chemotherapy (docetaxel) helps people with advanced non-small cell lung cancer whose disease got worse after prior treatment. Only 10 people enrolled before the study was stopped early. The goal …
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 26, 2026 04:23 UTC
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Experimental cocktail aims to reboot immune attack on tough cancers
Disease control TerminatedThis early-phase study tested a drug called plinabulin combined with radiation and immunotherapy in 19 people with advanced cancers (like lung, bladder, or melanoma) that had stopped responding to standard immunotherapy. The goal was to see if the combination was safe and could s…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 04:15 UTC
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Experimental cancer combo trial halted early
Disease control TerminatedThis study tested a combination of two immunotherapy drugs (BMS-986218 and nivolumab) plus precise radiation for people with advanced solid tumors that had spread. The goal was to see if this approach could help control the cancer and check for side effects. Only 13 people took p…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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New combo therapy for tough lung cancer shows early promise in safety study
Disease control TerminatedThis early-phase trial tested a combination of two immunotherapy drugs (atezolizumab and varlilumab) plus radiation in 16 people with advanced non-small cell lung cancer that had stopped responding to prior treatment. The main goal was to check safety and side effects. The study …
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated May 20, 2026 11:57 UTC
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Promising lung cancer drug combo study halted early
Disease control TerminatedThis study tested several targeted drugs (ALK inhibitors) and chemotherapy in people with a specific type of advanced lung cancer called ALK-positive non-squamous non-small cell lung cancer. The goal was to see which treatment worked best based on the patient's tumor markers. Onl…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 18, 2026 12:06 UTC
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Cancer brain metastasis drug combo trial halted early
Disease control TerminatedThis study tested two drugs, bintrafusp alfa and pimasertib, in people whose cancer had spread to the brain. The goal was to find the best dose and see if the combination could slow or stop tumor growth. The trial was stopped early after enrolling only 8 participants, so no clear…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Can meal timing protect your brain during cancer radiation?
Symptom relief TerminatedThis study tested a mobile app that helps people with brain metastases from breast or lung cancer follow a time-restricted eating plan (eating only during certain hours). The goal was to see if this approach could reduce memory and thinking problems after stereotactic radiosurger…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Symptom relief
Last updated May 22, 2026 14:01 UTC