STAGE IIIB LUNG CANCER AJCC V8
Clinical trials for STAGE IIIB LUNG CANCER AJCC V8 explained in plain language.
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New drug cocktail takes aim at resistant lung cancer
Disease control OngoingThis early-phase trial is testing whether combining two drugs—brigatinib and bevacizumab—can help people with a specific kind of lung cancer (ALK-positive non-small cell lung cancer) whose cancer has gotten worse despite previous ALK-targeted therapy. The study involves just 5 pa…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 23, 2026 19:18 UTC
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New combo therapy targets tough lung cancer in early trial
Disease control OngoingThis early-phase study tests the safety and best dose of a new drug, minnelide, when given with the standard drug osimertinib for people with advanced EGFR-mutated non-small cell lung cancer. The trial enrolls about 8 adults whose cancer has spread or cannot be removed by surgery…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 18, 2026 11:52 UTC
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Experimental combo aims to boost Radiation's punch against returning lung tumors
Disease control OngoingThis early-stage study tests a drug called NBTXR3, which makes cancer cells more sensitive to radiation, combined with a second round of radiation for people whose non-small cell lung cancer has returned and cannot be surgically removed. The main goal is to find the safest dose a…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 18, 2026 11:51 UTC
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Microwave vs. scalpel: new study seeks best way to treat lung tumors
Disease control OngoingThis study compares two treatments for lung lesions in people with non-small cell lung cancer, sarcoma, or colorectal cancer that has spread. One treatment uses microwaves to heat and kill tumor cells, while the other is a surgery to remove a small piece of lung. Researchers want…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 18, 2026 11:51 UTC
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Lung cancer trial aims to boost survival with immunotherapy combo
Disease control OngoingThis study tests whether adding the immunotherapy drug durvalumab to standard chemoradiation, and continuing it afterward, helps people with stage III lung cancer that cannot be surgically removed live longer and keep the cancer from coming back. About 660 adults with newly diagn…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 16, 2026 12:52 UTC
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New drug duo aims to control aggressive lung and nerve cancers
Disease control OngoingThis study tests two drugs together for people with small cell lung cancer or other high-grade neuroendocrine cancers that have already been treated. Niraparib blocks a DNA repair protein in cancer cells, while dostarlimab helps the immune system attack the tumor. The goal is to …
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 18:54 UTC
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New combo aims to control lung cancer when immunotherapy fails
Disease control OngoingThis phase 2 study tests a new drug (pevonedistat) combined with two standard chemotherapies (carboplatin and paclitaxel) in 27 adults with advanced non-small cell lung cancer that has not responded to immunotherapy. The goal is to see if this combination can shrink or control th…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 09, 2026 12:06 UTC
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Could zapping tumors with radiation boost immunotherapy in tough-to-treat lung cancer?
Disease control TerminatedThis study looks at whether adding radiation therapy to standard immunotherapy (with or without chemo) helps people with advanced non-small cell lung cancer that lacks the PD-L1 marker. About 427 adults with stage IIIB, IIIC, or IV cancer will be randomly assigned to get either t…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 08, 2026 13:18 UTC
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New online program aims to ease emotional burden for women battling lung cancer
Symptom relief OngoingThis study tests an online program called BREATHE for women with non-small cell lung cancer. The program uses mindfulness, compassion, and emotional processing to help improve social well-being and reduce distress. About 70 women will participate, and the main goal is to see if t…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 23, 2026 11:56 UTC
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New hope for cancer patients: drug targets appetite loss and wasting
Symptom relief OngoingThis study looks at whether a drug called anamorelin can help improve appetite and stop weight loss in people with advanced lung cancer who have lost their appetite and are losing weight. About 25 participants will take either the drug or a placebo and share their experiences thr…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2, PHASE3 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 22, 2026 12:08 UTC
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Smart radiation planning may ease lung cancer treatment side effects
Symptom relief OngoingThis study looks at whether updating radiation treatment plans at set times (adaptive planning) can lower side effects like lung inflammation in people with stage II-IV non-small cell lung cancer. About 34 participants will receive standard radiation and immunotherapy, but their …
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Symptom relief
Last updated Jun 12, 2026 12:04 UTC
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New Nurse-Led program aims to ease fear in advanced cancer patients
Symptom relief OngoingThis study tests a nurse-led program designed to help people with advanced lung or gynecologic cancer cope with fears about their future. About 42 participants will try the program, which includes sessions and home activities. The goal is to see if the program is practical and he…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated Jun 05, 2026 12:07 UTC
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One-and-Done radiation: a new hope for lung cancer patients after surgery?
Symptom relief OngoingThis early-stage study tests whether giving a single, very focused dose of radiation after lung cancer surgery is safe and causes fewer side effects than standard weeks-long radiation. It involves 50 adults with non-small cell lung cancer who had surgery but still have cancer cel…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: Roswell Park Cancer Institute • Aim: Symptom relief
Last updated Jun 01, 2026 17:55 UTC
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Massive lung cancer study aims to match genes to best treatments
Knowledge-focused OngoingThis large study is screening 8,300 people with early-stage non-small cell lung cancer that has been or will be removed by surgery. Researchers collect blood and tumor samples to look for genetic changes. The goal is to help doctors pick the right targeted therapy or immunotherap…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: NA • Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:58 UTC