STAGE III OVARIAN CANCER AJCC V8
Clinical trials for STAGE III OVARIAN CANCER AJCC V8 explained in plain language.
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New hope for hard-to-treat cancers? drug targets gene glitches in advanced tumors
Disease control OngoingThis phase 2 study tests the drug pembrolizumab in 21 people with advanced solid tumors that have specific gene changes (BRCA1, BRCA2, POLE, or POLD1). The goal is to see if the drug can shrink or stop the cancer from growing. This is not a cure, but a way to control the disease.
Matched conditions: STAGE III OVARIAN CANCER AJCC V8
Phase: PHASE2 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated May 01, 2026 15:29 UTC
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New drug duo targets BRCA cancers in early trial
Disease control OngoingThis early-phase trial tests a combination of two drugs—niraparib and dostarlimab—in people with breast, pancreas, or ovarian cancers that have a BRCA gene mutation and have spread or can't be removed by surgery. Niraparib blocks a DNA repair process that cancer cells rely on, wh…
Matched conditions: STAGE III OVARIAN CANCER AJCC V8
Phase: PHASE1 • Sponsor: University of Washington • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
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New drug combo shows promise in Tough-to-Treat cancers
Disease control OngoingThis early-phase study tests a new drug (BAY 1895344) combined with standard chemotherapy in people with advanced solid tumors, especially bladder cancer. The goal is to find the best dose and see if the combination is safe and tolerable. About 74 participants will receive the dr…
Matched conditions: STAGE III OVARIAN CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 30, 2026 15:51 UTC
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New drug shows promise in shrinking ovarian tumors before surgery
Disease control OngoingThis early-phase trial tests the drug olaparib in 15 people with newly diagnosed BRCA-mutant ovarian, fallopian tube, or peritoneal cancer. Participants take olaparib for two cycles before their planned surgery to see if it can shrink tumors safely. The goal is to find out if thi…
Matched conditions: STAGE III OVARIAN CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 29, 2026 15:03 UTC
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Cancer fear study pulled before starting
Knowledge-focused TerminatedThis study was designed to see if an online mental health program could help women with advanced gynecologic or breast cancer cope with the fear of their cancer coming back or getting worse. It planned to compare the program to standard educational materials. However, the study w…
Matched conditions: STAGE III OVARIAN CANCER AJCC V8
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:51 UTC