STAGE IB BREAST CANCER

This phase II trial tested a 9-day course of whole breast radiation (hypofractionated radiotherapy) in 102 patients with early-stage breast cancer (stages 0-IIB). The goal was to see if a shorter treatment schedule could maintain good cosmetic outcomes and quality of life while r…

This pilot study tested whether giving a high dose of targeted radiation (APBI) before surgery is feasible for older patients with early-stage, hormone-positive breast cancer. Twenty-two patients received the radiation followed by a lumpectomy. The goal was to see if this approac…

This study tested a combination of two drugs, fulvestrant and palbociclib, in older patients with hormone-sensitive breast cancer who either couldn't have surgery or chose not to. The goal was to see if the treatment could control the cancer for at least a year without needing su…

This study looked at whether shutting down the ovaries (ovarian suppression) combined with hormone therapy (tamoxifen or exemestane) could better prevent breast cancer from coming back in premenopausal women with hormone-sensitive breast cancer. Over 3,000 women who had surgery t…

This study looked at whether two anti-inflammatory drugs—fish oil and celecoxib (an arthritis medication)—can reduce inflammation and slow cancer spread in women with pregnancy-associated breast cancer. 42 women aged 18-50 with various stages of breast cancer took the drugs for a…

This study looked at whether having a breast MRI before surgery helps women with early-stage breast cancer get better surgical results. About 317 women with certain types of breast cancer took part. The goal was to see if the MRI could reduce the need for repeat surgeries and imp…