Targeted radiation before breast cancer surgery shows promise in small study
NCT ID NCT02186470
First seen Oct 31, 2025 · Last updated Jun 20, 2026 · Updated 36 times
Summary
This pilot study tested whether giving a high dose of targeted radiation (APBI) before surgery is feasible for older patients with early-stage, hormone-positive breast cancer. Twenty-two patients received the radiation followed by a lumpectomy. The goal was to see if this approach could shrink the tumor and reduce the amount of healthy tissue removed. The study focused on whether the treatment plan was reproducible and safe in the short term.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
accelerated partial breast irradiation (APBI)
What this could lead to
If successful, this approach could allow smaller surgeries and less damage to healthy breast tissue for certain breast cancer patients.
What could go wrong
This is a very small, early feasibility study with only 22 participants. It does not prove that this approach is better than standard care, and long-term outcomes are not yet known.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.