STAGE I PROSTATE CANCER AJCC V8

This study is testing if a very low dose of the drug apalutamide can lower PSA levels in men with prostate cancer before they have surgery to remove the prostate. PSA is a marker in the blood that can indicate how active the cancer is. The goal is to see if this low-dose approach…

This study is testing whether a dietary supplement made from white button mushrooms can help control prostate cancer. It is for men whose cancer has returned after initial treatment (showing rising PSA levels) and for men with newly diagnosed, low-risk cancer who are being monito…

This study aimed to test a combination of three treatments for men with high-risk prostate cancer that has not spread. The approach combined a drug to boost the immune system (pembrolizumab) with standard hormone-blocking therapy and radiation. The goal was to see if this combina…

This study compares two different radiation treatments for early-stage prostate cancer that hasn't spread. One treatment places a temporary radioactive seed inside the prostate, while the other delivers precise external radiation over five sessions. The main goal is to see which …

This study is testing if giving testosterone replacement therapy (TRT) to men with low testosterone and early-stage prostate cancer is safe and improves their quality of life. The men are on 'active surveillance,' which means their cancer is being closely monitored instead of bei…

This study compares two radiation schedules given after prostate cancer surgery. It tests whether a shorter, more intense 4.5-week course works as well as the standard 7-week course at keeping cancer from returning. Researchers will track side effects and quality of life for up t…

This study is testing whether adding a simple surgical step called vesicopexy during robot-assisted prostate cancer surgery helps men regain bladder control faster. Researchers will compare two groups of men: one receiving the standard surgery and one receiving the surgery with t…

This study is testing a lifestyle support program called 'Watchful Living' for Black and Hispanic men with early-stage prostate cancer who are on active surveillance (watching and waiting) and their partners. The program provides phone coaching on exercise and nutrition over six …

This study is testing a lifestyle program designed for African American men who have finished treatment for prostate cancer and their spouses or partners. The goal is to see if working together as a couple can help improve quality of life, increase physical activity, and encourag…

This study is testing whether it's practical for men with intermediate-risk prostate cancer to follow a strict Mediterranean diet for four weeks before their scheduled surgery. The main goal is to see if patients can stick to the diet and to measure how it affects their body chem…

This study aims to understand how certain prostate cancer hormone treatments affect heart health. It will compare two different hormone drugs given alongside radiation therapy to see which might be safer for the heart. Researchers will use heart scans and blood tests to learn why…

This study aims to understand the daily ups and downs of stress, social support, and healthy habits like exercise and diet in Black men who have survived prostate cancer and their partners. Researchers are observing how couples cope with stress together and how that affects their…