SPASTICITY

This pilot study tests whether focused shockwave therapy can reduce spasticity (involuntary muscle tightness) in the arms and hands of people with spinal cord injury. Twelve participants will receive three weekly sessions of the therapy, applied to the forearm and elbow muscles. …

This study tests a mild, non-invasive electrical stimulation on the lower back to see if it can reduce spasticity (muscle stiffness) in children with cerebral palsy. Thirty children aged 5 to 17 will receive the stimulation during movement exercises. Researchers will measure chan…

This study tests whether a full-body stimulation suit used at home can reduce spasticity (muscle stiffness) and ataxia (poor coordination) in people with multiple sclerosis. About 70 participants will either use the suit for 6 weeks plus usual care, or receive usual care alone. T…

This study tests a new medicine called IPN10200 for adults with arm muscle stiffness (spasticity) after a stroke or traumatic brain injury. The goal is to find the safest and most effective dose to reduce stiffness and improve movement. About 240 participants will receive either …

This study tests if freezing specific shoulder nerves (cryoneurolysis) can reduce pain and improve movement in people with spasticity from stroke, multiple sclerosis, or brain injury. About 50 adults will receive either one nerve-freezing session or standard Botox injections, the…

This study is testing a portable, wearable exoskeleton that helps stretch the legs and improve walking in people with spasticity caused by spinal cord injury. Ten veterans will wear the device during stretching, treadmill, and overground walking exercises. The goal is to see if t…

This pilot study looks at how botulinum toxin (Botox) injections affect the muscles, tendons, and nerves in the feet of people who have had a stroke and developed a tight, twisted foot (equinovarus). Researchers will use special ultrasound and movement tests to track these change…

This study is gathering information from 4500 people who have or will have brain surgery for conditions like aneurysms, tumors, epilepsy, and Parkinson's disease. The goal is to find patterns that help doctors predict how well someone will recover. By standardizing how outcomes a…

This study looks at how muscle stiffness (spasticity) patterns in the arms and legs of people with multiple sclerosis relate to their quality of life. Researchers will classify these patterns and measure their impact using patient surveys and physical tests. The goal is to better…