SOLID TUMOR

This first-in-human study aims to test the safety and find the right dose of a new radioactive drug called RYZ401 for people with advanced neuroendocrine tumors and other solid tumors. The treatment delivers radiation directly to cancer cells that have specific markers. The study…

This study is testing a new drug called ZGGS34 in people with advanced solid tumors that have not responded to standard treatments. The first part will find a safe dose, and the second part will see if the drug, sometimes given with chemotherapy, can help control cancer in people…

This study is testing an experimental drug called atamparib in adults with advanced lung cancer or other solid tumors that have spread. It aims to find the safest dose and see if the drug can shrink tumors in people who have already tried standard treatments and have a specific g…

This study is testing whether the drug olaparib can help control recurrent triple-negative breast cancer in patients who don't have the typical BRCA gene mutations. The trial will enroll 30 women with advanced breast cancer that has returned or spread. Researchers want to see if …

This is an early safety study for a new drug called BSI-082, designed for adults with advanced solid tumors that have spread or stopped responding to standard treatments. The study has two parts: first testing BSI-082 alone at increasing doses, then testing it combined with anoth…

This early-phase study is testing a new type of cell therapy called TCR-T for people with advanced solid tumors that have specific KRAS gene mutations. It aims to see if it is safe and if it can help control the cancer. The treatment involves collecting a patient's own immune cel…

This early-stage clinical trial is testing a new drug called HRS-8364 in adults with advanced solid tumors that have progressed despite standard treatments. The study aims to find a safe and effective dose and see if the drug can shrink tumors. It will enroll up to 282 participan…

This early-stage clinical trial is testing a new personalized mRNA vaccine designed to teach the immune system to attack a specific protein found in a patient's tumor cells. The vaccine is given in combination with an existing immunotherapy drug (anti-PD-1) to boost the body's ca…

This early-stage study is testing a new combination of two drugs for people with advanced solid tumors that have stopped responding to standard immunotherapy. The goal is to find the safest and most effective dose of the drug 5-Azacitidine when added to a patient's current immuno…

This study is testing if a natural product made from freeze-dried miracle fruit can help people who are having taste problems from their cancer treatment. About 45 adults with solid tumor cancers will take the berry product up to four times a day before meals for 90 days. Researc…

This study is creating a large collection of biological samples from people with hereditary cancers or a family history of cancer. Researchers will use these samples to grow tumor models in the lab to better understand how hereditary cancers develop and respond to treatments. Par…