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New hope for hard-to-treat breast cancer: drug targets hidden genetic switch

NCT ID NCT05522491

First seen Jan 03, 2026 · Last updated May 20, 2026 · Updated 19 times

Summary

This study tests the drug olaparib in 30 women with advanced triple-negative breast cancer that has come back or spread. Unlike other studies, these patients do not have the usual BRCA gene mutations but have a different change (BRCA1 promoter methylation) that may make the cancer sensitive to olaparib. The goal is to see if the drug can shrink tumors and delay cancer growth.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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