SOFT TISSUE SARCOMA (STS)

This study compares a new type of radiation therapy (SFRT) to standard radiation for people with large soft tissue sarcomas (tumors at least 5 cm). About 106 participants will be randomly assigned to one of the two treatments. The goal is to see if SFRT can shrink tumors better a…

This study tests whether a higher dose of proton radiation can better control soft tissue sarcomas that cannot be surgically removed. About 40 adults in Norway will receive radiation over 4 weeks, with the highest dose focused on the tumor center. The main goal is to see if the t…

This study tests an experimental oral drug called cirtuvivint in about 25 people with advanced soft-tissue sarcoma that has not responded to prior treatment. The goal is to see if the drug can stop or slow tumor growth for at least three months. Cirtuvivint works by blocking cert…

This study collects lung fluid and tissue samples from 70 people with soft-tissue sarcoma who are already having lung surgery. Researchers will look for specific inflammatory markers (NETs) in the fluid to see if they can predict how far the cancer has spread. The goal is to bett…

This study is gathering tissue samples and medical information from 800 people with high-risk soft tissue sarcomas. The goal is to learn how to personalize chemotherapy before surgery, using genetic and protein profiles. Participants either receive standard chemo plus surgery or …

This early-phase study tests whether a new radioactive tracer can help doctors see tumors on PET/CT scans. About 32 adults with different solid tumors will receive a single injection of the tracer. The goal is to understand where the tracer goes in the body, how it is cleared, an…