Sjogren syndrome
Clinical trials for Sjogren syndrome explained in plain language.
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Insulin-spiked eye drops may ease stubborn dry eye in Sjögren's patients
Disease control CompletedThis trial tests whether adding insulin to autologous serum eye drops (made from a patient's own blood) improves symptoms and signs of moderate to severe dry eye in people with autoimmune conditions like Sjögren's syndrome. Researchers will compare standard serum drops against se…
Matched conditions: SJOGREN SYNDROME
Phase 3 • Sponsor: Instituto de Oftalmología Fundación Conde de Valenciana • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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New drug shows promise in Late-Stage Sjogren's trial
Disease control CompletedThis phase 3 study tests whether the drug ianalumab can reduce disease activity in people with active Sjogren's syndrome. About 275 adults with the condition will receive either ianalumab or a placebo shot under the skin. The main goal is to see if the drug improves symptoms and …
Matched conditions: SJOGREN SYNDROME
Phase 3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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New Sjögren's drug shows promise in small study
Disease control CompletedThis study tested a drug called ianalumab in 21 adults with Sjögren's syndrome, an autoimmune disease that causes dry eyes and mouth. The goal was to understand how the drug works in the salivary glands and check its safety. Participants received injections of ianalumab and had b…
Matched conditions: SJOGREN SYNDROME
Phase 2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Nose stimulator could be new hope for Sjogren's dry eyes
Symptom relief CompletedThis pilot study tested a device that gently stimulates the inside of the nose to see if it can improve tear production in people with Sjogren's syndrome. 26 participants used either the active device or a sham (fake) device for 6 weeks, then everyone used the active device for a…
Matched conditions: SJOGREN SYNDROME
Sponsor: Abilion Medical Systems AB • Aim: Symptom relief
Last updated Jun 26, 2026 12:36 UTC
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Farming exposures under the microscope: massive health study follows 90,000 participants
Knowledge-focused CompletedThis study follows nearly 90,000 farmers and their spouses to track long-term health effects of pesticides, crops, and animals. Participants report new medical conditions, which researchers then confirm through medical records and genetic samples. The goal is to better understand…
Matched conditions: SJOGREN SYNDROME
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Scientists investigate immune cell role in rare IgG4 disease
Knowledge-focused CompletedThis study looked at a rare disease called IgG4-related disease, which causes swelling and scarring in organs. Researchers compared immune cells in the blood of 75 people: those with the disease, those with Sjogren syndrome, and healthy volunteers. The goal was to better understa…
Matched conditions: SJOGREN SYNDROME
Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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New study checks if pelvic floor survey works for Sjögren's patients
Knowledge-focused CompletedThis study looked at whether a pelvic floor symptom questionnaire (PFDI-20) is valid and reliable for people with primary Sjögren's syndrome. Ten adults with the condition completed the survey along with other health assessments. The goal was to see if the questionnaire accuratel…
Matched conditions: SJOGREN SYNDROME
Sponsor: Pamukkale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Sjögren's patients face hidden jaw pain, new study reveals
Knowledge-focused CompletedThis study looked at 27 adults with Sjögren's syndrome to find out how common jaw joint problems (TMD) are and if they relate to disease activity. Researchers measured jaw function, mouth opening, head posture, and oral health. The goal was to better understand the link between S…
Matched conditions: SJOGREN SYNDROME
Sponsor: Pamukkale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC