Short bowel syndrome
Clinical trials for Short bowel syndrome explained in plain language.
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New weekly shot shows promise for gut disorder patients
Disease control CompletedThis study tests the long-term safety and effectiveness of a weekly injection called glepaglutide in adults with short bowel syndrome, a condition where the body cannot absorb nutrients properly. Participants who completed a previous trial will receive the drug for about 2 years.…
Matched conditions: SHORT BOWEL SYNDROME
Phase 3 • Sponsor: Zealand Pharma • Aim: Disease control
Last updated Sep 10, 2026 00:00 UTC
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New drug could help people with short bowel syndrome ditch IV nutrition
Disease control CompletedThis phase 3 trial tests the long-term safety of glepaglutide, a drug that mimics a natural gut hormone, in 145 adults with short bowel syndrome. The goal is to see if it can safely help the gut absorb more nutrients, potentially reducing the need for intravenous feeding. Partici…
Matched conditions: SHORT BOWEL SYNDROME
Phase 3 • Sponsor: Zealand Pharma • Aim: Disease control
Last updated Sep 10, 2026 00:00 UTC
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New drug teduglutide monitored in 250 patients with short bowel syndrome
Disease control CompletedThis study follows 250 people in Japan with short bowel syndrome who are receiving teduglutide (Revestive) injections. Researchers will monitor side effects and how well the drug controls symptoms over 36 months. The goal is to see if teduglutide can safely reduce the need for in…
Matched conditions: SHORT BOWEL SYNDROME
Sponsor: Takeda • Aim: Disease control
Last updated Aug 09, 2026 00:00 UTC
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Growth hormone shows promise for weaning kids off IV nutrition
Disease control CompletedThis study tested whether giving growth hormone to children with short bowel syndrome could help them reduce or stop needing IV nutrition. Fourteen children aged 3-18 who had been on IV nutrition for at least 3 years took part. The results will show if the hormone improves intest…
Matched conditions: SHORT BOWEL SYNDROME
Phase 3 • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Could fiber be the key to better gut health for short bowel patients?
Disease control CompletedThis completed study looked at whether specific dietary fibers can improve nutrition and gut barrier function in people with short bowel syndrome. Ten adults with type II or III short bowel syndrome took dietary fiber, and researchers measured changes in blood and stool samples. …
Matched conditions: SHORT BOWEL SYNDROME
Sponsor: Jinling Hospital, China • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Daily injection could free kids from IV nutrition dependency
Disease control CompletedThis study tested a daily injection called teduglutide (Revestive) in 25 children aged 2 to 18 with short bowel syndrome who rely on IV nutrition. The goal was to see if the drug helps their intestines absorb more nutrients, so they can reduce or stop IV feedings. Researchers mea…
Matched conditions: SHORT BOWEL SYNDROME
Phase 4 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 26, 2026 15:47 UTC
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Can an amino acid pill help the body build protein when the gut fails?
Symptom relief CompletedResearchers are testing whether taking citrulline by mouth helps people with intestinal failure build protein more effectively. The study includes adults with short bowel syndrome who are fed orally and not on parenteral nutrition. Participants receive either citrulline or a plac…
Matched conditions: SHORT BOWEL SYNDROME
Phase 3 • Sponsor: Nantes University Hospital • Aim: Symptom relief
Last updated Sep 16, 2026 00:00 UTC
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Scientists map gut hormone changes after bowel surgery
Knowledge-focused CompletedThis study looked at how removing parts of the small intestine affects gut hormone levels after eating. Researchers measured these hormones in 39 people with different types of bowel resection and compared them to healthy controls. The goal was to better understand digestion and …
Matched conditions: SHORT BOWEL SYNDROME
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Nighttime feeding vs daytime: which is better for sleep and sugar levels?
Knowledge-focused CompletedThis study looked at 20 adults with short bowel syndrome who rely on home parenteral nutrition. Researchers compared giving the nutrition overnight versus during the day to see if timing affects blood sugar levels and sleep quality. Participants wore glucose monitors and activity…
Matched conditions: SHORT BOWEL SYNDROME
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC